TG Therapeutics (TGTX.US) Price Target 2026/2027: 20% Upside – Rating and Stock Analysis

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TG Therapeutics Price Target 2026: Analysts See 20% Upside

The average price target for TG Therapeutics is $77.50. This price target represents the analysts' view of the stock price over the next 12 months. The stock may be undervalued, because the price target is higher than the current price. The stock is 20.14% below the target, which can point to potential returns within the next 12 months if the analysts' view proves right. Also consider the stock's valuation ratios such as P/E, P/S and P/B, plus the technical analysis further down the page, for the full picture.
⚠️ Don’t buy a stock just because of its price targetA price target is the analysts’ estimate of where the stock will trade in 12 months. That estimate is often wrong. A large study of US stocks from 2000 to 2009 found that only 38% of price targets had been met after 12 months. On average, the targets promised 15 percentage points more return than the stocks delivered. Use the price target together with the financials and the trend, not on its own.Source: Bradshaw, Brown and Huang (2013)

Is TG Therapeutics overvalued or undervalued?

TG Therapeutics is currently undervalued with a gap of 20.1% relative to the price target.


The current price is $64.51, which places TG Therapeutics in the undervalued category. The stock is considered undervalued when the price is below $69.75, and overvalued when the price exceeds $85.25.


The fair value range is defined as ±10% of the price target, because price targets are estimates rather than exact values. For TG Therapeutics, the fair value range lies between $69.75 and $85.25.


See the full price target analysis for TG Therapeutics →

Analyst Ratings for TG Therapeutics stock in 2026: Strong Buy

8 analysts cover TG Therapeutics. There is broad agreement on a positive view — 87.5% recommend buying. The average price target is $77.50, which gives an upside of 20.1% from the current price.

Consensus: Strong Buy (4.50/5)
Strong Buy
6 (75%)
Buy
1 (12.5%)
Sell
1 (12.5%)
Strong Sell Sell Hold Buy Strong Buy
4.50 out of 5 based on 8 analysts

About TG Therapeutics – Biotechnology

TG Therapeutics, Inc., a commercial stage biopharmaceutical company, focuses on the acquisition, development, and commercialization of novel treatments for B-cell mediated diseases in the United States and internationally. The company provides BRIUMVI, an anti-CD20 monoclonal antibody for the treatment of adult patients with relapsing forms of multiple sclerosis (RMS), including clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease in adults. The company's development pipeline comprises Ublituximab IV, glycoengineered anti-CD20 mAb for the treatment of relapsing MS; TG-1701 is an orally available and covalently bound Bruton's tyrosine kinase (BTK) inhibitor that exhibits selectivity to BTK in vitro kinase screening; and TG-1801, a bispecific CD47 and CD19 antibody. Its research pipeline includes various investigational medicines. The company has license agreements with LFB Biotechnologies S.A.S; GTC Biotherapeutics; LFB/GTC LLC; Ildong Pharmaceutical Co. Ltd.; and Jiangsu Hengrui Medicine Co. The company was incorporated in 1993 and is based in Morrisville, North Carolina. Read more about the company

Key Figures for TG Therapeutics

$9.8B Market cap
$898M Revenue
Biotechnology Industry
96.36 P/E
10.87 P/S
17.36 P/B
United States Listed on exchange

What kind of stock is TG Therapeutics?

Quality stock Momentum stock

TG Therapeutics is classified as a quality stock and momentum stock. This means the stock combines several attractive traits, strong financial health (Piotroski 7/9), and strong price momentum.

Score Overview for TG Therapeutics

💰 Value Score 7/100 (Very Low)
⭐ Quality Score 74/100 (High)
🚀 Momentum Score 97/100 (Very High)
📊 Total Score 59/100

⚠️ 3 red flags identified 2 critical

Our analysis has identified 3 potential risk factors in TG Therapeutics that investors should be aware of.

⚠️ High debt: The debt-to-equity ratio is 160% – the company carries considerably more debt than equity, which raises the financial risk.
🚨 High short interest: 27.7% of the shares are sold short – many professional investors are betting on price declines.
🚨 Falling earnings: Quarterly earnings have fallen 86% year over year – the company's profitability is under pressure.

📈 Valuation

TG Therapeutics trades at a P/E ratio of 96.4, which is above the market average. The forward P/E is 30.4 (68% lower), which suggests the market expects rising earnings. The P/S ratio is 10.9 (high — the market pays a premium for the revenue). The P/B ratio is 17.4. The PEG ratio is 1.61.

💵 Profitability & Growth

TG Therapeutics has a profit margin of 11.8% (solid) and an operating margin of 21.5%. Return on equity (ROE) is 18.0% — solid return on equity. Return on assets (ROA) is 9.2%. The latest quarterly earnings grew -85.6% year over year — falling earnings.

🏦 Financial Health

The Piotroski score is 7 out of 9 — good financial health. Altman Z2 is 3.10 (healthy balance sheet — low risk). The debt-to-equity ratio (D/E) is 159.8% — moderate debt.

🚀 Momentum & Short Interest

Short interest is 27.66% — very high, the market is skeptical.

Insider Trading in TG Therapeutics 2026: Only sells

In 2026, insiders at TG Therapeutics have made 20 transactions – split into 2 purchases and 18 sales. On a net basis, insiders took $7,516,953 out of the stock. Active insiders include WEISS MICHAEL S, Echelard Yann, Charney Laurence N and others. Over the last 3 months: only sells.

Last 3 Months: Only sells

Insiders have exclusively sold shares over the last 3 months.

Over the last 3 months: 0 purchases and 1 sales. A net $274,800 out of the stock.

All Transactions: Mostly sells

Insiders have sold considerably more than they have bought. At large companies this can be due to planned sales (10b5-1 plans) and is not necessarily a negative signal.

Across the last 20 transactions: 2 purchases and 18 sales. A net $7,516,953 out of the stock.

Latest purchase: WEISS MICHAEL S bought 100,000 shares at $10.13 each on 2023-08-11. The stock has since risen 536.8%.

Latest sale: Charney Laurence N sold 5,000 shares at $54.96 each on 2026-09-10.

Who is buying: WEISS MICHAEL S, Echelard Yann.

Who is selling: Charney Laurence N, Echelard Yann, Lonial Sagar, Power Sean A.

Latest Insider Trades in TG Therapeutics (2026)

The table shows the last 20 reported insider transactions in TG Therapeutics. Green rows are purchases, red rows are sales. The data is based on official filings.

Transaction date Name Type Number of shares Price per share (USD) Total amount (USD)
2026-09-10 Charney Laurence N Sell 5,000 54.96 274,800
2025-11-24 Echelard Yann Sell 5,000 32.57 162,850
2025-09-11 Lonial Sagar Sell 20,852 32.24 672,268
2025-06-13 Echelard Yann Sell 10,000 36.94 369,400
2025-01-06 Power Sean A Sell 10,021 28.53 285,899
2025-01-03 Power Sean A Sell 11,337 30.29 343,398
2024-11-11 Lonial Sagar Sell 5,000 30.44 152,200
2024-11-11 Charney Laurence N Sell 25,000 30.20 755,000
2024-11-05 Echelard Yann Sell 20,000 24.48 489,600
2024-06-20 Lonial Sagar Sell 16,348 16.87 275,791

Who is buying and selling TG Therapeutics shares in 2026?

The following insiders have bought shares in TG Therapeutics: WEISS MICHAEL S, Echelard Yann. In total, $1,108,760 was bought across 2 transactions. The following insiders have sold shares: Charney Laurence N, Echelard Yann, Lonial Sagar, Power Sean A. In total, $8,625,713 was sold across 18 transactions. Insider trades are legal transactions in which executives and board members buy or sell shares of their own company. These transactions are reported to the SEC and are publicly available.

TG Therapeutics Short Selling 2026: 27.7% Sold Short

Extremely shorted: 27.7% of the free float
Short % of free float
27.7%
Assessment
Extremely shorted
Short squeeze risk
Very High
Data source
EODHD
Reported about twice a month
The stock has an extremely high share of short selling. More than 20% of the freely traded shares are sold short, which is unusual and can point to great skepticism among institutional investors. The risk of a short squeeze on positive news is considerable.

What does this mean for you as an investor?
A short interest of 27.7% means that 27.7% of the freely traded shares in TG Therapeutics have been borrowed and sold by investors betting on falling prices. On positive surprises (e.g. a strong earnings report), short sellers can be forced to buy back shares quickly to close their positions, which can cause a short squeeze with sharp price gains in a short time.

The next potential catalyst is the earnings report on Mar 1, 2027. With a short interest of 27.7%, the report can trigger considerable volatility.

Short interest comes from our data provider EODHD. The figure is reported about twice a month; we check it every trading day.
Short Interest Scale
0% 2% 5% 10% 20%+
Low Moderate High Very High Extreme
▲
27.7%

When Does TG Therapeutics Report Earnings – Next Date: Mar 1, 2027

The next earnings report from TG Therapeutics is scheduled for March 1, 2027, before the market opens. This report covers the fourth quarter (Q4), which ended on December 31, 2026.



Technical Analysis of TG Therapeutics 2026 – Signal: Strong Buy

Overall Technical Signal: Strong Buy

Based on trend analysis (SMA50/SMA200) and MACD trend (positive/negative on a daily + weekly basis). Updated November 14, 2026.

Trend Analysis of TG Therapeutics, Inc

TG Therapeutics, Inc is in a short-term uptrend. The price of $64.51 is 9.4% above the 20-day average ($58.94). Medium term, the picture is positive: the price is 13.8% above the 50-day average ($56.70). Long term, the stock is 42.2% above the 200-day average ($45.38), which confirms a long-term uptrend.

Golden Cross: The 50-day average (56.70) is above the 200-day average (45.38), which is a classic bullish signal for TG Therapeutics, Inc.

Is TG Therapeutics, Inc overbought or oversold?

TG Therapeutics, Inc has an RSI of 65.4. The stock shows positive momentum in the upper part of the neutral zone. Combined with the positive trend, this supports the bullish picture.

MACD Analysis for TG Therapeutics, Inc

Daily MACD: MACD is positive (2.526), which means the short-term trend is bullish (the 12-day EMA is above the 26-day EMA). MACD is above the signal line (1.874) by 0.652, which confirms rising momentum in the uptrend.

Weekly MACD: MACD5 is positive (4.626), which indicates a broader bullish long-term trend. MACD5 is above the signal line (4.464) by 0.162, which confirms rising long-term momentum.

Overall MACD assessment: Both the daily and weekly MACD are positive and above their signal lines. Trend and momentum confirm each other across time horizons – the strongest bullish signal.

Risk Profile for TG Therapeutics, Inc

TG Therapeutics, Inc has an annual standard deviation of 46.1%, which classifies the stock as medium risk. The price can swing noticeably when the market moves.

Overall Technical Conclusion for TG Therapeutics, Inc

Trend: Positive. The price trades above SMA50 and SMA200.

MACD trend (zero line): Daily bullish (2.526). Weekly bullish (4.626).

MACD momentum (signal): Daily rising. Weekly rising.

RSI: 65.4 – neutral.

Technical signal: Strong Buy

The price is in an uptrend (above SMA50/SMA200) and MACD is positive on both a daily and weekly basis. Trend and MACD trend confirm each other – the strongest technical buy signal.

Who Owns TG Therapeutics?

The three largest owners of TG Therapeutics are BlackRock Inc (14.4%), Vanguard Portfolio Management, LLC (5.2%) and State Street Corp (5.1%). The percentage is their share of the stock, as of Jun 30, 2026. Source: our data provider EODHD.

The 10 Largest Institutions

InstitutionStakeChange
BlackRock Inc14.41%−0.9%
Vanguard Portfolio Management, LLC5.20%−3.8%
State Street Corp5.09%−10.0%
Vanguard Capital Management, LLC4.02%−6.9%
Geode Capital Management, LLC2.38%+4.1%
D. E. Shaw & Co LP2.22%+476.4%
Soleus Capital Management, L.P.1.91%−27.3%
T. Rowe Price Associates, Inc.1.81%+337.4%
ClearBridge Advisors, LLC1.73%−17.5%
Congress Asset Management Company, LLP1.70%+19.9%

As of Jun 30, 2026. "Change" is the change in shares held since the holder's previous report.

The 5 Largest Funds

FundStakeChange
iShares Core S&P Small-Cap ETF5.57%−0.1%
Vanguard MStar Total Stk Mkt Idx Invest2.87%+0.3%
iShares Russell 2000 ETF2.41%0.0%
Vanguard Small Cap Index2.02%−2.2%
State Street® SPDR® S&P® Biotech ETF1.90%+2.7%

As of Oct 30, 2026. A fund may be managed by one of the institutions above, so the two lists cannot be added together.

Frequently Asked Questions About TG Therapeutics stock in 2026

Should you buy TG Therapeutics stock now?
Yes, the technical signal for TG Therapeutics is currently Strong Buy. TG Therapeutics trades at $64.51 as of Nov 14, 2026. The technical analysis shows the following: MACD is positive (bullish trend) at 2.526 with rising momentum (signal: 1.874); RSI is at 65.4 (neutral zone); the stock is in a short-term uptrend (price above the 20-day average); the analyst price target of $77.50 points to 20.1% upside. The stock is in a broader uptrend (above SMA50/SMA200). This is a technical observation based on current data, not investment advice.
What is the price target for TG Therapeutics stock?
The average analyst price target for TG Therapeutics is $77.50. The current price is $64.51, which gives an upside of 20.1%. Based on this, the stock is considered undervalued. The fair value range (±10% of the price target) is between $69.75 and $85.25.
Is TG Therapeutics a dividend stock?
No, TG Therapeutics does not currently pay a dividend to shareholders. The company reinvests its profits in growth instead of paying dividends.
What is the risk of TG Therapeutics stock?
TG Therapeutics is rated as a stock in the risk category Moderate. the annual standard deviation is 46.1%, which classifies the stock as Moderate.
Is TG Therapeutics overvalued?
No, TG Therapeutics is considered undervalued based on the analyst price target (20.1% upside). TG Therapeutics has the following valuation ratios: a P/E ratio of 96.4 (highly valued), a P/S ratio of 10.9, a P/B ratio of 17.4. The analyst price target suggests that the stock is undervalued by 20.1%.
Is TG Therapeutics overbought?
No, TG Therapeutics is not overbought. RSI is at 65.4 (neutral zone). The technical indicators show: RSI is at 65.4 (upper neutral zone), which shows positive momentum but is not yet overbought. In addition, the price is 9.4% above the 20-day average (short-term uptrend). In addition, MACD is positive with rising momentum (bullish).
When is the next TG Therapeutics earnings report?
TG Therapeutics reports its next earnings on March 1, 2027. The stock currently trades at $64.51. With a P/E ratio of 96.4, the market will be watching closely whether earnings meet expectations. The RSI is at 65.4, so the report can reinforce the current technical trend.
Is TG Therapeutics shorted?
Yes, TG Therapeutics is shorted with 27.7% of the free float sold short. This is an extremely high level of short selling, which points to great skepticism among institutional investors. The risk of a short squeeze on positive news or earnings is very high. The figure comes from our data provider EODHD, is reported about twice a month, and we check it every trading day.
Are insiders buying TG Therapeutics stock?
No, insiders are not buying TG Therapeutics shares – they are net sellers. Over the last 3 months, insiders have made 0 purchases and 1 sales. On a net basis, 274,800 USD worth of shares were sold. Across the last 20 reported transactions, the split is 2 purchases and 18 sales, with a net 7,516,953 USD sold. Active sellers include Charney Laurence N, Echelard Yann, Lonial Sagar and others. Insider selling can have several explanations (e.g. planned 10b5-1 sales, portfolio diversification or taxes), but sustained selling by several insiders is worth watching closely.
Is TG Therapeutics a good stock?
Based on our total score, TG Therapeutics is rated as a mediocre stock with a total score of 59 out of 100. The stock scores around average on value, quality and momentum – it sits near the median in our database. The score is made up of Value: 7/100, Quality: 74/100, Momentum: 97/100. In addition: analysts see 20.1% upside to the price target. Whether now is the time to buy is a separate question: the technical signal is Strong Buy. Whether TG Therapeutics is a good investment depends on your time horizon, risk profile and portfolio. This is a data-driven observation, not investment advice.
What is the outlook for TG Therapeutics stock?
The outlook for TG Therapeutics based on current data: the average analyst price target is $77.50 (+20.1%); the stock is in an uptrend (above SMA50 and SMA200); the next earnings report is due on Mar 1, 2027, which can move the price; the P/E ratio is 96.4 (high – the market expects growth). Keep in mind that stock prices are affected by many factors, including earnings reports, the economy and market sentiment. Past returns are no guarantee of future returns.
Why is TG Therapeutics stock rising?
TG Therapeutics is rising right now. The technical indicators show: the price is 9.4% above the 20-day average; MACD is positive with rising momentum (bullish signal); short interest is 27.7% (high – many are betting on a decline); insiders have mostly been selling the stock recently. For the latest context, see our technical analysis and insider section above.
How high can TG Therapeutics go?
The average analyst price target for TG Therapeutics is $77.50, which corresponds to a potential gain of 20.1% from the current price of $64.51. The stock has traded between $26.76 and $68.03 over the last 52 weeks. Keep in mind that price targets are estimates, not guarantees. Actual price moves depend on earnings, market conditions and unexpected events.
How low can TG Therapeutics fall?
The stock has traded as low as $26.76 over the last 52 weeks — that is 58.5% below the current price of $64.51. The biggest decline (drawdown) in the same period was 60.7% from high to low. Within a year, the price typically swings about ±46.1% (standard deviation — a measure of price swings). A difficult year could therefore mean a further decline of that size. Remember: past price swings are no guarantee for the future — a stock can fall further than the last 52 weeks suggest, especially on profit warnings, sector crises or a market crash. Use stop-loss orders and spread your portfolio to limit losses in single stocks.
What does TG Therapeutics do?
TG Therapeutics, Inc., a commercial stage biopharmaceutical company, focuses on the acquisition, development, and commercialization of novel treatments for B-cell mediated diseases in the United States and internationally. The company provides BRIUMVI, an anti-CD20 monoclonal ... The company belongs to the Healthcare sector, more specifically the Biotechnology industry, is headquartered in United States, and is traded on the USA Stocks. See the key figures, earnings history and price development above to evaluate TG Therapeutics as an investment.
Did TG Therapeutics raise or lower its guidance?
Over the last 60 days we have not registered a guidance raise or cut from TG Therapeutics. The company can still adjust its guidance at quarterly reports or between reports — see the earnings history above.
Is TG Therapeutics making money or losing money?
Yes, TG Therapeutics is making money, not losing it. The company has a profit margin (the share of revenue left over as profit) of 11.8% — which is solid. The operating margin (profit before interest and taxes) is 21.5%. At a P/E ratio of 96.4, you currently pay 96.4 dollars for every dollar of the company's annual earnings. A consistently profitable company is usually more resilient than growth stocks that are not yet making money.
Can TG Therapeutics go bankrupt?
The bankruptcy risk of TG Therapeutics is rated as low. Altman Z2 (a model for assessing financial distress) is 3.10 — that places the company in the healthy zone. The company has a healthy balance sheet with limited debt relative to earnings and assets. The Piotroski score (financial health 0-9, higher is better) is 7 — which is strong. Debt relative to equity is 160% (high). Remember: models like Altman Z2 are statistical — unexpected shocks (fraud, a sector collapse, lawsuits) can always happen. Spread your portfolio.
Does TG Therapeutics have a lot of debt?
Yes, TG Therapeutics has elevated debt relative to equity. The debt-to-equity ratio (D/E — interest-bearing debt to equity) is 160%. For the healthcare sector, anything above 150% counts as elevated — that raises the financial risk, especially if interest rates rise or earnings fall. In healthcare, 80-150% is typical — large pharma companies carry debt for research and acquisitions. Note: D/E levels are highly sector-specific — a bank at 300% debt is normal, a tech stock at 300% is extremely leveraged. Always compare with similar companies in the same sector. Can TG Therapeutics service its debt? Can service its debt without problems — the interest coverage ratio (how many times earnings can cover interest payments) is 5.7x, and net debt equals 1.7 years of earnings (EBITDA).

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