Tenaya Therapeutics (TNYA.US) Price Target 2026/2027: 330% Upside – Rating and Stock Analysis

0.75
Share this analysis:

Tenaya Therapeutics Price Target 2026: Analysts See 328% Upside

The average price target for Tenaya Therapeutics is $3.20. This price target represents the analysts' view of the stock price over the next 12 months. The stock may be undervalued, because the price target is higher than the current price. The stock is 328.49% below the target, which can point to potential returns within the next 12 months if the analysts' view proves right. Also consider the stock's valuation ratios such as P/E, P/S and P/B, plus the technical analysis further down the page, for the full picture.

Is Tenaya Therapeutics overvalued or undervalued?

Tenaya Therapeutics is currently undervalued with a gap of 328.5% relative to the price target.


The current price is $0.75, which places Tenaya Therapeutics in the undervalued category. The stock is considered undervalued when the price is below $2.88, and overvalued when the price exceeds $3.52.


The fair value range is defined as ±10% of the price target, because price targets are estimates rather than exact values. For Tenaya Therapeutics, the fair value range lies between $2.88 and $3.52.


See the full price target analysis for Tenaya Therapeutics →

Analyst Ratings for Tenaya Therapeutics stock in 2026: Strong Buy

9 analysts cover Tenaya Therapeutics. There is broad agreement on a positive view — 100% recommend buying. The average price target is $3.20, which gives an upside of 328.5% from the current price.

Consensus: Strong Buy (4.67/5)
Strong Buy
6 (66.7%)
Buy
3 (33.3%)
Strong Sell Sell Hold Buy Strong Buy
4.67 out of 5 based on 9 analysts

About Tenaya Therapeutics – Bioteknologi

Tenaya Therapeutics, Inc., a clinical-stage biotechnology company, discovers, develops, and delivers therapies for heart disease in the United States. Its lead product candidate includes TN-201, a gene therapy for myosin binding protein C3-associated hypertrophic cardiomyopathy that is in Phase 1b/2 clinical trial; TN-401, a gene therapy for plakophilin 2-associated arrhythmogenic right ventricular cardiomyopathy, which is in Phase 1b/2 clinical trial; and TN-301, a small molecule histone deacetylase-6 for heart failure with preserved ejection fraction that is in phase 1 clinical trial. The company develops its products through gene addition, gene editing, gene silencing, and cellular regeneration. It has a research collaboration agreement with Alnylam Pharmaceuticals, Inc. to identify and validate novel gene targets for the potential treatment of cardiovascular disease. Tenaya Therapeutics, Inc. was incorporated in 2016 and is headquartered in South San Francisco, California. Read more about the company

Key Figures for Tenaya Therapeutics

$ 163M Market cap
$ 225K Revenue
Bioteknologi Industry
- P/E
724.31 P/S
2.35 P/B
USA Listed on exchange

What kind of stock is Tenaya Therapeutics?

Speculative stock

Tenaya Therapeutics is classified as a speculative stock.

⚠️ 4 red flags identified 2 critical

Our analysis has identified 4 potential risk factors in Tenaya Therapeutics that investors should be aware of.

⚠️ Weak financial health: The Piotroski score is only 3/9 – the company shows signs of weakened profitability, liquidity or capital structure.
🚨 Weak balance sheet (elevated risk): Altman Z2 is -22.96 – the balance sheet is measurably weaker than average. This is a risk signal based on the numbers, not a bankruptcy prediction.
🚨 Negative return on equity: ROE is -73.6% – the company is generating a negative return for shareholders.
⚠️ High short interest: 14.9% of the shares are sold short – many professional investors are betting on price declines.

📈 Valuation

The P/S ratio is 724.3 (high — the market pays a premium for the revenue). The P/B ratio is 2.3.

🏦 Financial Health

The Piotroski score is 3 out of 9 — weak financial health, be careful. Altman Z2 is -22.96 (weak balance sheet — elevated risk). The debt-to-equity ratio (D/E) is 29.2% — low debt, a solid balance sheet.

🚀 Momentum & Short Interest

Short interest is 14.93% — very high, the market is skeptical.

Insider Trading in Tenaya Therapeutics 2026: The Signal Is negative

In 2026, insiders at Tenaya Therapeutics have made 20 transactions, all of which were sales. On a net basis, insiders took 2,812,450 $ out of the stock. Active insiders include Tingley Whittemore, Higa Tomohiro, Ali Faraz and others. In the short term (last 3 months), the insider signal is negative.

Short-Term Signal (3 months): Negative

Insiders have exclusively sold shares over the last 3 months.

Over the last 3 months: 0 purchases and 3 sales. A net 6,317 $ out of the stock.

Long-Term Signal (all transactions): Negative

Insiders have exclusively sold shares in the recent period. This can suggest management sees limited opportunity.

Across the last 20 transactions: 0 purchases and 20 sales. A net 2,812,450 $ out of the stock.

Latest sale: Tingley Whittemore sold 3,121 shares at 1 $ each on 2026-05-18.

Who is selling: Tingley Whittemore, Higa Tomohiro, Ali Faraz, COLUMN GROUP III GP, LP.

Latest Insider Trades in Tenaya Therapeutics (2026)

The table shows the last 20 reported insider transactions in Tenaya Therapeutics. Green rows are purchases, red rows are sales. The data is based on official filings.

Transaction date Name Type Number of shares Price per share ($) Total amount ($)
2026-05-18 Tingley Whittemore Sell 3,121 1 2,466
2026-05-18 Higa Tomohiro Sell 1,485 1 1,173
2026-05-18 Ali Faraz Sell 3,390 1 2,678
2026-02-25 COLUMN GROUP III GP, LP Sell 1,649,281 1 923,597
2026-02-24 COLUMN GROUP III GP, LP Sell 309,228 1 191,721
2026-02-23 COLUMN GROUP III GP, LP Sell 143,709 1 86,225
2026-02-20 COLUMN GROUP III GP, LP Sell 245,965 1 150,039
2026-02-17 Tingley Whittemore Sell 1,642 1 1,051
2026-02-17 Higa Tomohiro Sell 611 1 391
2026-02-17 Ali Faraz Sell 5,851 1 3,745

Who is buying and selling Tenaya Therapeutics shares in 2026?

The following insiders have sold shares: Tingley Whittemore, Higa Tomohiro, Ali Faraz, COLUMN GROUP III GP, LP. In total, 2,812,450 $ was sold across 20 transactions. Insider trades are legal transactions in which executives and board members buy or sell shares of their own company. These transactions are reported to the SEC and are publicly available.

Tenaya Therapeutics Short Selling 2026: 14.9% Sold Short

Very high short interest: 14.9% of the free float
Short % of free float
14.9%
Assessment
Very high short interest
Short squeeze risk
High
Data source
SEC
Updated daily
The stock has a very high share of short selling. Between 10-20% of the freely traded shares are sold short, which points to considerable bearish sentiment. A positive earnings report or unexpectedly good news can trigger a short squeeze with sharp price gains.

What does this mean for you as an investor?
A short interest of 14.9% means that 14.9% of the freely traded shares in Tenaya Therapeutics have been borrowed and sold by investors betting on falling prices. On positive surprises (e.g. a strong earnings report), short sellers can be forced to buy back shares quickly to close their positions, which can cause a short squeeze with sharp price gains in a short time.

Data is updated daily based on official filings with the SEC.
Short Interest Scale
0% 2% 5% 10% 20%+
Low Moderate High Very High Extreme
14.9%

When Does Tenaya Therapeutics Report Earnings?

The next earnings date for Tenaya Therapeutics is not yet available. Check the company's investor calendar for more information.



Technical Analysis of Tenaya Therapeutics 2026 – Signal: Strong Sell

Overall Technical Signal: Strong Sell

Based on trend analysis (SMA50/SMA200) and MACD trend (positive/negative on a daily + weekly basis). Updated August 11, 2026.

Trend Analysis of Tenaya Therapeutics Inc. Common Stock

Tenaya Therapeutics Inc. Common Stock is in a short-term downtrend. The price of $0.74 is 5.1% below the 20-day average ($0.78). Medium term, the picture is negative: the price is 4.4% below the 50-day average ($0.77). Long term, the stock is 15.1% below the 200-day average ($0.87), which signals a long-term downtrend.

Death Cross: The 50-day average (0.77) is below the 200-day average (0.87), which is a classic bearish signal for Tenaya Therapeutics Inc. Common Stock.

Is Tenaya Therapeutics Inc. Common Stock overbought or oversold?

Tenaya Therapeutics Inc. Common Stock has an RSI of 44.2. The stock sits in the lower part of the neutral zone, which points to weak momentum without being oversold. In the current downtrend, be careful about reading this as a buying opportunity.

MACD Analysis for Tenaya Therapeutics Inc. Common Stock

Daily MACD: MACD is negative (-0.016), which means the short-term trend is bearish (the 12-day EMA is below the 26-day EMA). MACD is below the signal line (-0.010) by 0.006, which confirms growing negative momentum in the downtrend.

Weekly MACD: MACD5 is negative (-0.033), which indicates a broader bearish long-term trend. MACD5 is above the signal line (-0.044) by 0.011, which suggests the negative long-term momentum is fading – a bigger trend reversal could be ahead.

Overall MACD assessment: Both the daily and weekly trend are bearish (MACD negative). However, momentum shows signs of improving on a weekly basis – a potential trend reversal could be ahead, but it is not confirmed yet.

Risk Profile for Tenaya Therapeutics Inc. Common Stock

Tenaya Therapeutics Inc. Common Stock has an annual standard deviation of 0.0%, which classifies the stock as low risk. Price swings are limited, and the stock suits conservative investors.

Overall Technical Conclusion for Tenaya Therapeutics Inc. Common Stock

Trend: Negative. The price trades below SMA50 and SMA200.

MACD trend (zero line): Daily bearish (-0.016). Weekly bearish (-0.033).

MACD momentum (signal): Daily falling. Weekly rising.

RSI: 44.2 – neutral.

Technical signal: Strong Sell

The price is in a downtrend (below SMA50/SMA200) and MACD is negative on both a daily and weekly basis. Avoid buying and consider closing existing positions.

Frequently Asked Questions About Tenaya Therapeutics stock in 2026

Should you buy Tenaya Therapeutics stock now?
No, the technical signal for Tenaya Therapeutics is currently SELL. Tenaya Therapeutics trades at $0.75 as of 8/11/2026. The overall technical signal is: Strong Sell. The technical analysis shows the following: MACD is negative (bearish trend) at -0.016 with falling momentum (signal: -0.010); RSI is at 44.2 (neutral zone); the stock is in a short-term downtrend (price below the 20-day average); the analyst price target of $3.20 points to 328.5% upside. The stock is in a broader downtrend (below SMA50/SMA200). Buying in a downtrend is generally not recommended. This is a technical observation based on current data, not investment advice.
What is the price target for Tenaya Therapeutics stock?
The average analyst price target for Tenaya Therapeutics is $3.20. The current price is $0.75, which gives an upside of 328.5%. Based on this, the stock is considered undervalued. The fair value range (±10% of the price target) is between $2.88 and $3.52.
Is Tenaya Therapeutics a dividend stock?
No, Tenaya Therapeutics does not currently pay a dividend to shareholders. The company reinvests its profits in growth instead of paying dividends.
What is the risk of Tenaya Therapeutics stock?
Tenaya Therapeutics is rated as a stock with low risk. the annual standard deviation is 0.0%, which classifies the stock as low risk.
Is Tenaya Therapeutics overvalued?
No, Tenaya Therapeutics is considered undervalued based on the analyst price target (328.5% upside). Tenaya Therapeutics has the following valuation ratios: a P/S ratio of 724.3, a P/B ratio of 2.3. The analyst price target suggests that the stock is undervalued by 328.5%.
Is Tenaya Therapeutics overbought?
No, Tenaya Therapeutics is not overbought. RSI is at 44.2 (neutral zone). The technical indicators show: RSI is at 44.2 (neutral zone between 30-70), which signals neither overbought nor oversold. In addition, the price is 3.9% below the 20-day average (short-term downtrend). In addition, MACD is negative with falling momentum (bearish).
When is the next Tenaya Therapeutics earnings report?
The date of the next earnings report for Tenaya Therapeutics has not been published yet. Check the company's investor calendar for updates.
Is Tenaya Therapeutics shorted?
Yes, Tenaya Therapeutics is shorted with 14.9% of the free float sold short. This is a very high level of short selling, which points to considerable bearish sentiment. A positive earnings report or unexpectedly good news can trigger a short squeeze with sharp price gains. Data is updated daily based on official filings with the SEC.
Are insiders buying Tenaya Therapeutics stock?
No, insiders are not buying Tenaya Therapeutics shares – they are net sellers. Over the last 3 months, insiders have made 0 purchases and 3 sales. On a net basis, 6,317 $ worth of shares were sold. Across the last 20 reported transactions, the split is 0 purchases and 20 sales, with a net 2,812,450 $ sold. Active sellers include Tingley Whittemore, Higa Tomohiro, Ali Faraz and others. Insider selling can have several explanations (e.g. planned 10b5-1 sales, portfolio diversification or taxes), but sustained selling by several insiders is worth watching closely.
Is Tenaya Therapeutics a good stock?
We do not yet have enough data to give Tenaya Therapeutics an overall rating. In addition: analysts see 328.5% upside to the price target; technical signal: Strong Sell. Whether Tenaya Therapeutics is a good investment depends on your time horizon, risk profile and portfolio. This is a data-driven observation, not investment advice.
What is the outlook for Tenaya Therapeutics stock?
The outlook for Tenaya Therapeutics based on current data: the average analyst price target is $3.20 (+328.5%); the stock is in a downtrend (below SMA50 and SMA200). Keep in mind that stock prices are affected by many factors, including earnings reports, the economy and market sentiment. Past returns are no guarantee of future returns.
Why is Tenaya Therapeutics stock falling?
Tenaya Therapeutics is falling right now. The technical indicators show: the price is 3.9% below the 20-day average; MACD is negative with falling momentum (bearish signal); short interest is 14.9% (high – many are betting on a decline); insiders have mostly been selling the stock recently. For the latest context, see our technical analysis, insider section and news overview above.
How high can Tenaya Therapeutics go?
The average analyst price target for Tenaya Therapeutics is $3.20, which corresponds to a potential gain of 328.5% from the current price of $0.75. Keep in mind that price targets are estimates, not guarantees. Actual price moves depend on earnings, market conditions and unexpected events.
How low can Tenaya Therapeutics fall?
We lack enough history to give a specific floor for Tenaya Therapeutics. Remember: past price swings are no guarantee for the future — a stock can fall further than the last 52 weeks suggest, especially on profit warnings, sector crises or a market crash. Use stop-loss orders and spread your portfolio to limit losses in single stocks.
What does Tenaya Therapeutics do?
Tenaya Therapeutics, Inc., a clinical-stage biotechnology company, discovers, develops, and delivers therapies for heart disease in the United States. Its lead product candidate includes TN-201, a gene therapy for myosin binding protein C3-associated hypertrophic cardiomyopath... The company belongs to the Healthcare sector, more specifically the Bioteknologi industry, is headquartered in USA, and is traded on the USA Stocks. See the key figures, earnings history and price development above to evaluate Tenaya Therapeutics as an investment.
Did Tenaya Therapeutics raise or lower its guidance?
Over the last 60 days we have not registered a guidance raise or cut from Tenaya Therapeutics. The company can still adjust its guidance at quarterly reports or between reports — see the earnings history and the news overview above.
Is Tenaya Therapeutics making money or losing money?
We have no current profitability data for Tenaya Therapeutics. See the latest report in the earnings history above.
Can Tenaya Therapeutics go bankrupt?
The bankruptcy risk of Tenaya Therapeutics is rated as elevated. Altman Z2 (a model for assessing financial distress) is -22.96 — that places the company in the weak zone. This is a probability based on the numbers, not a verdict — bankruptcy is not imminent. But the balance sheet is measurably weaker than average, so watch the debt, liquidity and possible capital raises. The Piotroski score (financial health 0-9, higher is better) is 3 — which is weak. Debt relative to equity is 29% (low). Remember: models like Altman Z2 are statistical — unexpected shocks (fraud, a sector collapse, lawsuits) can always happen. Spread your portfolio.
Does Tenaya Therapeutics have a lot of debt?
No, Tenaya Therapeutics has low debt relative to equity. The debt-to-equity ratio (D/E — interest-bearing debt to equity) is 29%. For the healthcare sector, anything below 80% counts as low debt. In healthcare, 80-150% is typical — large pharma companies carry debt for research and acquisitions. Note: D/E levels are highly sector-specific — a bank at 300% debt is normal, a tech stock at 300% is extremely leveraged. Always compare with similar companies in the same sector.