Sana Biotechnology (SANA.US) Price Target 2026/2027: 120% Upside – Rating and Stock Analysis

3.85
Share this analysis:

Sana Biotechnology Price Target 2026: Analysts See 119% Upside

The average price target for Sana Biotechnology is $8.43. This price target represents the analysts' view of the stock price over the next 12 months. The stock may be undervalued, because the price target is higher than the current price. The stock is 119.25% below the target, which can point to potential returns within the next 12 months if the analysts' view proves right. Also consider the stock's valuation ratios such as P/E, P/S and P/B, plus the technical analysis further down the page, for the full picture.

Is Sana Biotechnology overvalued or undervalued?

Sana Biotechnology is currently undervalued with a gap of 119.2% relative to the price target.


The current price is $3.85, which places Sana Biotechnology in the undervalued category. The stock is considered undervalued when the price is below $7.59, and overvalued when the price exceeds $9.27.


The fair value range is defined as ±10% of the price target, because price targets are estimates rather than exact values. For Sana Biotechnology, the fair value range lies between $7.59 and $9.27.


See the full price target analysis for Sana Biotechnology →

Analyst Ratings for Sana Biotechnology stock in 2026: Buy

8 analysts cover Sana Biotechnology. There is broad agreement on a positive view — 87.5% recommend buying. The average price target is $8.43, which gives an upside of 119.2% from the current price.

Consensus: Buy (4.38/5)
Strong Buy
4 (50%)
Buy
3 (37.5%)
Hold
1 (12.5%)
Strong Sell Sell Hold Buy Strong Buy
4.38 out of 5 based on 8 analysts

About Sana Biotechnology – Bioteknologi

Sana Biotechnology, Inc., a biotechnology company, focuses on utilizing engineered cells as medicines in the United States. It develops ex vivo and in vivo cell engineering platforms for various therapeutic areas with unmet treatment needs, including type 1 diabetes, B cell mediated autoimmune diseases, and oncology. The company's product pipeline includes UP421, a HIP-modified allogeneic primary islet cell product, which is in phase 1 clinical trial to treat type 1 diabetes; SC451, a HIP-modified, stem cell derived pancreatic islet cell therapy, which is in preclinical trial for the treatment of type 1 diabetes; SG293 and SG299, a CD8-targeted fusosome for the treatment of B cell hematologic malignancies and B cell mediated autoimmune diseases. The company has an option and license agreement with Beam Therapeutics Inc. for use of Beam's proprietary CRISPR Cas12b nuclease editing technology to research, develop, and commercialize engineered cell therapy products; and a license agreement with Harvard College to access certain intellectual property for the development of hypoimmune-modified cells. The company has a strategic collaboration with Mayo Clinic for the development of SC451, a hypoimmune-modified pancreatic islet cell therapy for type 1 diabetes. The company was formerly known as FD Therapeutics, Inc. and changed its name to Sana Biotechnology, Inc. in September 2018. Sana Biotechnology, Inc. was incorporated in 2018 and is headquartered in Seattle, Washington. Read more about the company

Key Figures for Sana Biotechnology

$ 1.2B Market cap
- Revenue
Bioteknologi Industry
- P/E
- P/S
7.43 P/B
USA Listed on exchange
sana.com Website

What kind of stock is Sana Biotechnology?

Speculative stock

Sana Biotechnology is classified as a speculative stock.

Score Overview for Sana Biotechnology

💰 Value Score 5/100 (Very Low)
⭐ Quality Score 9/100 (Very Low)
🚀 Momentum Score 29/100 (Low)
📊 Total Score 14/100

⚠️ 4 red flags identified 3 critical

Our analysis has identified 4 potential risk factors in Sana Biotechnology that investors should be aware of.

⚠️ Weak financial health: The Piotroski score is only 2/9 – the company shows signs of weakened profitability, liquidity or capital structure.
🚨 Weak balance sheet (elevated risk): Altman Z2 is -16.81 – the balance sheet is measurably weaker than average. This is a risk signal based on the numbers, not a bankruptcy prediction.
🚨 Negative return on equity: ROE is -152.9% – the company is generating a negative return for shareholders.
🚨 High short interest: 24.0% of the shares are sold short – many professional investors are betting on price declines.

📈 Valuation

The P/B ratio is 7.4.

🏦 Financial Health

The Piotroski score is 2 out of 9 — weak financial health, be careful. Altman Z2 is -16.81 (weak balance sheet — elevated risk). The debt-to-equity ratio (D/E) is 100.0% — moderate debt.

🚀 Momentum & Short Interest

Short interest is 24.00% — very high, the market is skeptical.

Insider Trading in Sana Biotechnology 2026: The Signal Is negative

In 2026, insiders at Sana Biotechnology have made 20 transactions – split into 3 purchases and 17 sales. On a net basis, insiders put 3,541,195 $ into the stock, which is a positive signal. Active insiders include NELSEN ROBERT, CRANDELL KEITH, ARCH Venture Fund X, L.P. and others. In the short term (last 3 months), the insider signal is negative.

Short-Term Signal (3 months): Negative

Insiders have exclusively sold shares over the last 3 months.

Over the last 3 months: 0 purchases and 1 sales. A net 169,159 $ out of the stock.

Long-Term Signal (all transactions): Mostly positive

Insiders have bought considerably more than they have sold. This suggests several key people see value in the stock.

Across the last 20 transactions: 3 purchases and 17 sales. A net 3,541,195 $ into the stock.

Latest purchase: NELSEN ROBERT bought 363,637 shares at 6 $ each on 2024-02-08. The stock has since fallen 28.7%.

Latest sale: PATEL DHAVALKUMAR DHIRAJLAL sold 41,158 shares at 4 $ each on 2026-08-27.

Who is buying: NELSEN ROBERT, CRANDELL KEITH, ARCH Venture Fund X, L.P..

Who is selling: PATEL DHAVALKUMAR DHIRAJLAL, Wyrick Susan D., Harr Steve, Cassidy Bernard J, FMR LLC and others.

Latest Insider Trades in Sana Biotechnology (2026)

The table shows the last 20 reported insider transactions in Sana Biotechnology. Green rows are purchases, red rows are sales. The data is based on official filings.

Transaction date Name Type Number of shares Price per share ($) Total amount ($)
2026-08-27 PATEL DHAVALKUMAR DHIRAJLAL Sell 41,158 4 169,159
2026-03-09 Wyrick Susan D. Sell 3,342 3 10,360
2026-03-09 Harr Steve Sell 11,526 3 35,731
2026-03-03 Wyrick Susan D. Sell 491 4 1,920
2026-01-05 Wyrick Susan D. Sell 2,407 4 10,278
2025-12-15 Wyrick Susan D. Sell 873 5 4,557
2025-12-04 Wyrick Susan D. Sell 2,565 4 11,389
2025-06-04 Wyrick Susan D. Sell 2,567 2 5,955
2025-03-10 Wyrick Susan D. Sell 836 3 2,140
2025-03-10 Harr Steve Sell 12,820 3 32,819

Who is buying and selling Sana Biotechnology shares in 2026?

The following insiders have bought shares in Sana Biotechnology: NELSEN ROBERT, CRANDELL KEITH, ARCH Venture Fund X, L.P.. In total, 6,000,011 $ was bought across 3 transactions. The following insiders have sold shares: PATEL DHAVALKUMAR DHIRAJLAL, Wyrick Susan D., Harr Steve, Cassidy Bernard J, FMR LLC and others. In total, 2,458,815 $ was sold across 17 transactions. Insider trades are legal transactions in which executives and board members buy or sell shares of their own company. These transactions are reported to the SEC and are publicly available.

Sana Biotechnology Short Selling 2026: 24.0% Sold Short

Extremely shorted: 24.0% of the free float
Short % of free float
24.0%
Assessment
Extremely shorted
Short squeeze risk
Very High
Data source
SEC
Updated daily
The stock has an extremely high share of short selling. More than 20% of the freely traded shares are sold short, which is unusual and can point to great skepticism among institutional investors. The risk of a short squeeze on positive news is considerable.

What does this mean for you as an investor?
A short interest of 24.0% means that 24.0% of the freely traded shares in Sana Biotechnology have been borrowed and sold by investors betting on falling prices. On positive surprises (e.g. a strong earnings report), short sellers can be forced to buy back shares quickly to close their positions, which can cause a short squeeze with sharp price gains in a short time.

Data is updated daily based on official filings with the SEC.
Short Interest Scale
0% 2% 5% 10% 20%+
Low Moderate High Very High Extreme
24.0%

When Does Sana Biotechnology Report Earnings?

The next earnings date for Sana Biotechnology is not yet available. Check the company's investor calendar for more information.



Technical Analysis of Sana Biotechnology 2026 – Signal: Strong Buy

Overall Technical Signal: Strong Buy

Based on trend analysis (SMA50/SMA200) and MACD trend (positive/negative on a daily + weekly basis). Updated September 4, 2026.

Trend Analysis of Sana Biotechnology, Inc

Sana Biotechnology, Inc is in a short-term uptrend. The price of $3.92 is 2.4% above the 20-day average ($3.83). Medium term, the picture is positive: the price is 8.8% above the 50-day average ($3.60). Long term, the stock is 6.0% above the 200-day average ($3.70), which confirms a long-term uptrend.

Death Cross: The 50-day average (3.60) is below the 200-day average (3.70), which is a classic bearish signal for Sana Biotechnology, Inc.

Is Sana Biotechnology, Inc overbought or oversold?

Sana Biotechnology, Inc has an RSI of 55.5. The stock shows positive momentum in the upper part of the neutral zone. Combined with the positive trend, this supports the bullish picture.

MACD Analysis for Sana Biotechnology, Inc

Daily MACD: MACD is positive (0.125), which means the short-term trend is bullish (the 12-day EMA is above the 26-day EMA). MACD is below the signal line (0.137) by 0.012, which suggests the positive momentum is fading – the trend could be turning.

Weekly MACD: MACD5 is positive (0.037), which indicates a broader bullish long-term trend. MACD5 is above the signal line (-0.072) by 0.109, which confirms rising long-term momentum.

Overall MACD assessment: Both the daily and weekly trend are bullish (MACD positive). However, momentum shows signs of weakening on a daily basis. Watch whether the trend holds.

Risk Profile for Sana Biotechnology, Inc

Sana Biotechnology, Inc has an annual standard deviation of 84.7%, which classifies the stock as Extremely speculative. Only risk-tolerant investors should consider this stock, because the price swings can be very large.

Overall Technical Conclusion for Sana Biotechnology, Inc

Trend: Positive. The price trades above SMA50 and SMA200.

MACD trend (zero line): Daily bullish (0.125). Weekly bullish (0.037).

MACD momentum (signal): Daily falling. Weekly rising.

RSI: 55.5 – neutral.

Technical signal: Strong Buy

The price is in an uptrend (above SMA50/SMA200) and MACD is positive on both a daily and weekly basis. Trend and MACD trend confirm each other – the strongest technical buy signal.

Frequently Asked Questions About Sana Biotechnology stock in 2026

Should you buy Sana Biotechnology stock now?
Yes, the technical signal for Sana Biotechnology is currently BUY. Sana Biotechnology trades at $3.85 as of 9/4/2026. The overall technical signal is: Strong Buy. The technical analysis shows the following: MACD is positive (bullish trend) at 0.125 with falling momentum (signal: 0.137); RSI is at 55.5 (neutral zone); the stock is in a short-term uptrend (price above the 20-day average); the analyst price target of $8.43 points to 119.2% upside. The stock is in a broader uptrend (above SMA50/SMA200). This is a technical observation based on current data, not investment advice.
What is the price target for Sana Biotechnology stock?
The average analyst price target for Sana Biotechnology is $8.43. The current price is $3.85, which gives an upside of 119.2%. Based on this, the stock is considered undervalued. The fair value range (±10% of the price target) is between $7.59 and $9.27.
Is Sana Biotechnology a dividend stock?
No, Sana Biotechnology does not currently pay a dividend to shareholders. The company reinvests its profits in growth instead of paying dividends.
What is the risk of Sana Biotechnology stock?
Sana Biotechnology is rated as a stock in the risk category Extremely speculative. the annual standard deviation is 84.7%, which classifies the stock as Extremely speculative.
Is Sana Biotechnology overvalued?
No, Sana Biotechnology is considered undervalued based on the analyst price target (119.2% upside). Sana Biotechnology has the following valuation ratios: a P/B ratio of 7.4. The analyst price target suggests that the stock is undervalued by 119.2%.
Is Sana Biotechnology overbought?
No, Sana Biotechnology is not overbought. RSI is at 55.5 (neutral zone). The technical indicators show: RSI is at 55.5 (neutral zone between 30-70), which signals neither overbought nor oversold. In addition, the price is 0.5% above the 20-day average (short-term uptrend). In addition, MACD is positive, but momentum is falling.
When is the next Sana Biotechnology earnings report?
The date of the next earnings report for Sana Biotechnology has not been published yet. Check the company's investor calendar for updates.
Is Sana Biotechnology shorted?
Yes, Sana Biotechnology is shorted with 24.0% of the free float sold short. This is an extremely high level of short selling, which points to great skepticism among institutional investors. The risk of a short squeeze on positive news or earnings is very high. Data is updated daily based on official filings with the SEC.
Are insiders buying Sana Biotechnology stock?
No, insiders are not buying Sana Biotechnology shares – they are net sellers. Over the last 3 months, insiders have made 0 purchases and 1 sales. On a net basis, 169,159 $ worth of shares were sold. Across the last 20 reported transactions, the split is 3 purchases and 17 sales, with a net 3,541,195 $ bought. Active sellers include PATEL DHAVALKUMAR DHIRAJLAL, Wyrick Susan D., Harr Steve and others. Insider selling can have several explanations (e.g. planned 10b5-1 sales, portfolio diversification or taxes), but sustained selling by several insiders is worth watching closely.
Is Sana Biotechnology a good stock?
Based on our total score, Sana Biotechnology is rated as a disastrous stock with a total score of 14 out of 100. The stock scores very low on value, quality and momentum – it is among the worst in our database. The score is made up of Value: 5/100, Quality: 9/100, Momentum: 29/100. In addition: analysts see 119.2% upside to the price target; technical signal: Strong Buy. Whether Sana Biotechnology is a good investment depends on your time horizon, risk profile and portfolio. This is a data-driven observation, not investment advice.
What is the outlook for Sana Biotechnology stock?
The outlook for Sana Biotechnology based on current data: the average analyst price target is $8.43 (+119.2%); the stock is in an uptrend (above SMA50 and SMA200). Keep in mind that stock prices are affected by many factors, including earnings reports, the economy and market sentiment. Past returns are no guarantee of future returns.
Why is Sana Biotechnology stock moving?
Sana Biotechnology is stable right now. The technical indicators show: the price is close to the 20-day average; short interest is 24.0% (high – many are betting on a decline); insiders have mostly been selling the stock recently. For the latest context, see our technical analysis, insider section and news overview above.
How high can Sana Biotechnology go?
The average analyst price target for Sana Biotechnology is $8.43, which corresponds to a potential gain of 119.2% from the current price of $3.85. Keep in mind that price targets are estimates, not guarantees. Actual price moves depend on earnings, market conditions and unexpected events.
How low can Sana Biotechnology fall?
We lack enough history to give a specific floor for Sana Biotechnology. Remember: past price swings are no guarantee for the future — a stock can fall further than the last 52 weeks suggest, especially on profit warnings, sector crises or a market crash. Use stop-loss orders and spread your portfolio to limit losses in single stocks.
What does Sana Biotechnology do?
Sana Biotechnology, Inc., a biotechnology company, focuses on utilizing engineered cells as medicines in the United States. It develops ex vivo and in vivo cell engineering platforms for various therapeutic areas with unmet treatment needs, including type 1 diabetes, B cell me... The company belongs to the Healthcare sector, more specifically the Bioteknologi industry, is headquartered in USA, and is traded on the USA Stocks. See the key figures, earnings history and price development above to evaluate Sana Biotechnology as an investment.
Did Sana Biotechnology raise or lower its guidance?
Over the last 60 days we have not registered a guidance raise or cut from Sana Biotechnology. The company can still adjust its guidance at quarterly reports or between reports — see the earnings history and the news overview above.
Is Sana Biotechnology making money or losing money?
We have no current profitability data for Sana Biotechnology. See the latest report in the earnings history above.
Can Sana Biotechnology go bankrupt?
The bankruptcy risk of Sana Biotechnology is rated as elevated. Altman Z2 (a model for assessing financial distress) is -16.81 — that places the company in the weak zone. This is a probability based on the numbers, not a verdict — bankruptcy is not imminent. But the balance sheet is measurably weaker than average, so watch the debt, liquidity and possible capital raises. The Piotroski score (financial health 0-9, higher is better) is 2 — which is weak. Debt relative to equity is 100% (moderate). Remember: models like Altman Z2 are statistical — unexpected shocks (fraud, a sector collapse, lawsuits) can always happen. Spread your portfolio.
Does Sana Biotechnology have a lot of debt?
Sana Biotechnology has moderate debt relative to equity. The debt-to-equity ratio (D/E — interest-bearing debt to equity) is 100%. For the healthcare sector, 80-150% counts as a typical level. In healthcare, 80-150% is typical — large pharma companies carry debt for research and acquisitions. Note: D/E levels are highly sector-specific — a bank at 300% debt is normal, a tech stock at 300% is extremely leveraged. Always compare with similar companies in the same sector.