Personalis (PSNL.US) Price Target and Rating 2026/2027

13,35
-1,26%
Price history for Personalis (PSNL.US) – stock price at 13.35 $, August 2026
Personalis stock price – price development 2026. Updated Aug 6, 2026.
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Personalis Price Target 2026: Analysts See 4% Upside

The average price target for Personalis is $13.88. This price target represents the analysts' view of the stock price over the next 12 months. The stock may be undervalued, because the price target is higher than the current price. The stock is 3,97% below the target, which can point to potential returns within the next 12 months if the analysts' view proves right. Also consider the stock's valuation ratios such as P/E, P/S and P/B, plus the technical analysis further down the page, for the full picture.

Is Personalis overvalued or undervalued?

Personalis is currently fairly valued with a gap of 4% relative to the price target.


The current price is $13.35, which places Personalis in the fairly valued category. The stock is considered undervalued when the price is below $12.49, and overvalued when the price exceeds $15.27.


The fair value range is defined as ±10% of the price target, because price targets are estimates rather than exact values. For Personalis, the fair value range lies between $12.49 and $15.27.


See the full price target analysis for Personalis →

Analyst Ratings for Personalis stock in 2026: Buy

7 analysts cover Personalis. There is broad agreement on a positive view — 85.7% recommend buying. The average price target is $13.88, which gives an upside of 4% from the current price.

Consensus: Buy (4.43/5)
Strong Buy
4 (57.1%)
Buy
2 (28.6%)
Hold
1 (14.3%)
Strong Sell Sell Hold Buy Strong Buy
4.43 out of 5 based on 7 analysts

About Personalis – Diagnostics & Research

Personalis, Inc. develops, markets, and sells advanced cancer genomic tests and services in the United States and internationally. The company offers NeXT Personal, a tumor-informed liquid biopsy test for detection of minimal residual disease (MRD), therapy response and recurrence monitoring in solid tumor cancers; and ImmunoID NeXT, a tissue-based service that combines whole exome and whole transcriptome sequencing data with advanced analytics to provide a multi-dimensional view of the tumor and the tumor microenvironment from a single sample. It also provides NeXT Personal Dx, a tumor-informed liquid biopsy test for the detection of MRD; and NeXT Dx, a tumor profiling test that is used to help select therapy for a cancer patient and identify potential clinical trials for a patient. In addition, the company performs whole exome sequencing of cancer tissue and matched blood samples for diagnostic companies as an input to their products; and whole genome sequencing on human samples for research projects, such as population sequencing initiatives. Its services are used by pharmaceutical companies for translational research, biomarker discovery, the development of personalized cancer therapies, and for clinical trials, as well as tests are used by physicians to detect residual or recurrent cancer in patients, monitor cancer response to therapy, and uncover insights for therapy selection. The company's customers include pharmaceutical companies, biopharmaceutical companies, diagnostics companies, universities, non-profits, government entities, and patients. The company has strategic collaboration with Tempus AI, Inc. to bring ultra-sensitive cancer recurrence testing to colorectal cancer patients. Personalis, Inc. was incorporated in 2011 and is headquartered in Fremont, California. Read more about the company

Key Figures for Personalis

$ 1,4B Market cap
$ 64,5M Revenue
Diagnostics & Research Industry
- P/E
22.37 P/S
5.30 P/B
USA Listed on exchange
Sundhed Sector

What kind of stock is Personalis?

Momentum stock

Personalis is classified as a momentum stock with a momentum score in the top 9% of all stocks. The price has risen 0.0% over the long term.

Score Overview for Personalis

💰 Value Score 10/100 (Very Low)
⭐ Quality Score 1/100 (Very Low)
🚀 Momentum Score 91/100 (Very High)
📊 Total Score 34/100

⚠️ 5 red flags identified 4 critical

Our analysis has identified 5 potential risk factors in Personalis that investors should be aware of.

🚨 Weak financial health: The Piotroski score is only 1/9 – the company shows signs of weakened profitability, liquidity or capital structure.
🚨 Weak balance sheet (elevated risk): Altman Z2 is -0.39 – the balance sheet is measurably weaker than average. This is a risk signal based on the numbers, not a bankruptcy prediction.
🚨 Negative profit margin: The profit margin is -148.1% – the company is losing money on its operations.
🚨 Negative return on equity: ROE is -41.4% – the company is generating a negative return for shareholders.
⚠️ High short interest: 16.7% of the shares are sold short – many professional investors are betting on price declines.

📈 Valuation

The P/S ratio is 22.4 (high — the market pays a premium for the revenue). The P/B ratio is 5.3.

🏦 Financial Health

The Piotroski score is 1 out of 9 — weak financial health, be careful. Altman Z2 is -0.39 (weak balance sheet — elevated risk). The debt-to-equity ratio (D/E) is 33.2% — low debt, a solid balance sheet.

🚀 Momentum & Short Interest

Short interest is 16.74% — very high, the market is skeptical.

Insider Trading in Personalis 2026: The Signal Is negative

In 2026, insiders at Personalis have made 20 transactions – split into 7 purchases and 13 sales. On a net basis, insiders took 7,633,814 $ out of the stock. Active insiders include Tempus AI, Inc., Chen Richard, Hall Christopher M and others. In the short term (last 3 months), the insider signal is negative.

Short-Term Signal (3 months): Negative

Insiders have exclusively sold shares over the last 3 months.

Over the last 3 months: 0 purchases and 9 sales. A net 6,819,446 $ out of the stock.

Long-Term Signal (all transactions): Mostly negative

Insiders have sold considerably more than they have bought. At large companies this can be due to planned sales (10b5-1 plans) and is not necessarily a negative signal.

Across the last 20 transactions: 7 purchases and 13 sales. A net 7,633,814 $ out of the stock.

Latest purchase: Tempus AI, Inc. bought 28,000 shares at 9 $ each on 2025-12-22. The stock has since risen 51.4%.

Latest sale: Chen Richard sold 100,000 shares at 15 $ each on 2026-07-15.

Who is buying: Tempus AI, Inc..

Who is selling: Chen Richard, Hall Christopher M, Tachibana Aaron, Aaron Tachibana.

Latest Insider Trades in Personalis (2026)

The table shows the last 20 reported insider transactions in Personalis. Green rows are purchases, red rows are sales. The data is based on official filings.

Transaction date Name Type Number of shares Price per share ($) Total amount ($)
2026-07-15 Chen Richard Sell 100,000 15 1,515,000
2026-07-09 Hall Christopher M Sell 100,000 15 1,508,000
2026-06-29 Tachibana Aaron Sell 4,982 14 69,748
2026-06-26 Tachibana Aaron Sell 28,832 13 380,006
2026-06-26 Hall Christopher M Sell 100,000 13 1,315,000
2026-06-04 Tachibana Aaron Sell 40,000 12 480,400
2026-05-29 Tachibana Aaron Sell 38,799 12 449,292
2026-05-29 Hall Christopher M Sell 80,091 11 882,603
2026-05-28 Hall Christopher M Sell 19,909 11 219,397
2026-01-22 Tachibana Aaron Sell 1,201 12 13,812

Who is buying and selling Personalis shares in 2026?

The following insiders have bought shares in Personalis: Tempus AI, Inc.. In total, 1,448,337 $ was bought across 7 transactions. The following insiders have sold shares: Chen Richard, Hall Christopher M, Tachibana Aaron, Aaron Tachibana. In total, 9,082,151 $ was sold across 13 transactions. Insider trades are legal transactions in which executives and board members buy or sell shares of their own company. These transactions are reported to the SEC and are publicly available.

Personalis Short Selling 2026: 16.7% Sold Short

Very high short interest: 16.7% of the free float
Short % of free float
16.7%
Assessment
Very high short interest
Short squeeze risk
High
Data source
SEC
Updated daily
The stock has a very high share of short selling. Between 10-20% of the freely traded shares are sold short, which points to considerable bearish sentiment. A positive earnings report or unexpectedly good news can trigger a short squeeze with sharp price gains.

What does this mean for you as an investor?
A short interest of 16.7% means that 16.7% of the freely traded shares in Personalis have been borrowed and sold by investors betting on falling prices. On positive surprises (e.g. a strong earnings report), short sellers can be forced to buy back shares quickly to close their positions, which can cause a short squeeze with sharp price gains in a short time.

Data is updated daily based on official filings with the SEC.
Short Interest Scale
0% 2% 5% 10% 20%+
Low Moderate High Very High Extreme
16.7%

When Does Personalis Report Earnings?

The next earnings date for Personalis is not yet available. Check the company's investor calendar for more information.



Technical Analysis of Personalis 2026 – Signal: Strong Buy

Overall Technical Signal: Strong Buy

Based on trend analysis (SMA50/SMA200) and MACD trend (positive/negative on a daily + weekly basis). Updated August 6, 2026.

Technical analysis of Personalis (PSNL.US) – RSI 57, MACD positive (bullish), daily candlestick chart August 2026
Personalis technical analysis – candlestick chart with RSI and MACD. Updated Aug 6, 2026.

Trend Analysis of Personalis, Inc

Personalis, Inc is in a short-term uptrend. The price of $13.52 is 0.3% above the 20-day average ($13.48). Medium term, the picture is positive: the price is 11.0% above the 50-day average ($12.18). Long term, the stock is 48.4% above the 200-day average ($9.11), which confirms a long-term uptrend.

Golden Cross: The 50-day average (12.18) is above the 200-day average (9.11), which is a classic bullish signal for Personalis, Inc.

Is Personalis, Inc overbought or oversold?

Personalis, Inc has an RSI of 56.6. The stock shows positive momentum in the upper part of the neutral zone. Combined with the positive trend, this supports the bullish picture.

MACD Analysis for Personalis, Inc

Daily MACD: MACD is positive (0.154), which means the short-term trend is bullish (the 12-day EMA is above the 26-day EMA). MACD is below the signal line (0.247) by 0.093, which suggests the positive momentum is fading – the trend could be turning.

Weekly MACD: MACD5 is positive (1.543), which indicates a broader bullish long-term trend. MACD5 is above the signal line (1.020) by 0.523, which confirms rising long-term momentum.

Overall MACD assessment: Both the daily and weekly trend are bullish (MACD positive). However, momentum shows signs of weakening on a daily basis. Watch whether the trend holds.

Risk Profile for Personalis, Inc

Personalis, Inc has an annual standard deviation of 91.0%, which classifies the stock as extreme risk. Only risk-tolerant investors should consider this stock, because the price swings can be very large.

Overall Technical Conclusion for Personalis, Inc

Trend: Positive. The price trades above SMA50 and SMA200.

MACD trend (zero line): Daily bullish (0.154). Weekly bullish (1.543).

MACD momentum (signal): Daily falling. Weekly rising.

RSI: 56.6 – neutral.

Technical signal: Strong Buy

The price is in an uptrend (above SMA50/SMA200) and MACD is positive on both a daily and weekly basis. Trend and MACD trend confirm each other – the strongest technical buy signal.

Frequently Asked Questions About Personalis stock in 2026

Should you buy Personalis stock now?
Yes, the technical signal for Personalis is currently BUY. Personalis trades at $13.35 as of 8/6/2026. The overall technical signal is: Strong Buy. The technical analysis shows the following: MACD is positive (bullish trend) at 0.154 with falling momentum (signal: 0.247); RSI is at 56.6 (neutral zone); the stock is in a short-term downtrend (price below the 20-day average); the analyst price target of $13.88 points to 4.0% upside. The stock is in a broader uptrend (above SMA50/SMA200). This is a technical observation based on current data, not investment advice.
What is the price target for Personalis stock?
The average analyst price target for Personalis is $13.88. The current price is $13.35, which gives an upside of 4.0%. Based on this, the stock is considered fairly valued. The fair value range (±10% of the price target) is between $12.49 and $15.27.
Is Personalis a dividend stock?
No, Personalis does not currently pay a dividend to shareholders. The company reinvests its profits in growth instead of paying dividends.
What is the risk of Personalis stock?
Personalis is rated as a stock with extreme risk. the annual standard deviation is 91.0%, which classifies the stock as extreme risk.
Is Personalis overvalued?
Personalis is considered fairly valued – the price is close to the analyst price target. Personalis has the following valuation ratios: a P/S ratio of 22.4, a P/B ratio of 5.3. The stock trades close to the analyst price target and is considered fairly valued.
Is Personalis overbought?
No, Personalis is not overbought. RSI is at 56.6 (neutral zone). The technical indicators show: RSI is at 56.6 (neutral zone between 30-70), which signals neither overbought nor oversold. In addition, the price is 0.9% below the 20-day average (short-term downtrend). In addition, MACD is positive, but momentum is falling.
When is the next Personalis earnings report?
The date of the next earnings report for Personalis has not been published yet. Check the company's investor calendar for updates.
Is Personalis shorted?
Yes, Personalis is shorted with 16.7% of the free float sold short. This is a very high level of short selling, which points to considerable bearish sentiment. A positive earnings report or unexpectedly good news can trigger a short squeeze with sharp price gains. Data is updated daily based on official filings with the SEC.
Are insiders buying Personalis stock?
No, insiders are not buying Personalis shares – they are net sellers. Over the last 3 months, insiders have made 0 purchases and 9 sales. On a net basis, 6,819,446 $ worth of shares were sold. Across the last 20 reported transactions, the split is 7 purchases and 13 sales, with a net 7,633,814 $ sold. Active sellers include Chen Richard, Hall Christopher M, Tachibana Aaron and others. Insider selling can have several explanations (e.g. planned 10b5-1 sales, portfolio diversification or taxes), but sustained selling by several insiders is worth watching closely.
Is Personalis a good stock?
Based on our total score, Personalis is rated as a poor stock with a total score of 34 out of 100. The stock scores below average on value, quality and momentum – it sits at the lower end of the market. The score is made up of Value: 10/100, Quality: 1/100, Momentum: 91/100. In addition: technical signal: Strong Buy. Whether Personalis is a good investment depends on your time horizon, risk profile and portfolio. This is a data-driven observation, not investment advice.
What is the outlook for Personalis stock?
The outlook for Personalis based on current data: the average analyst price target is $13.88 (+4.0%); the stock is in an uptrend (above SMA50 and SMA200). Keep in mind that stock prices are affected by many factors, including earnings reports, the economy and market sentiment. Past returns are no guarantee of future returns.
Why is Personalis stock moving?
Personalis is stable right now. The technical indicators show: the price is close to the 20-day average; short interest is 16.7% (high – many are betting on a decline); insiders have mostly been selling the stock recently. For the latest context, see our technical analysis, insider section and news overview above.
How high can Personalis go?
The average analyst price target for Personalis is $13.88, which corresponds to a potential gain of 4.0% from the current price of $13.35. Keep in mind that price targets are estimates, not guarantees. Actual price moves depend on earnings, market conditions and unexpected events.
How low can Personalis fall?
We lack enough history to give a specific floor for Personalis. Remember: past price swings are no guarantee for the future — a stock can fall further than the last 52 weeks suggest, especially on profit warnings, sector crises or a market crash. Use stop-loss orders and spread your portfolio to limit losses in single stocks.
What does Personalis do?
Personalis, Inc. develops, markets, and sells advanced cancer genomic tests and services in the United States and internationally. The company offers NeXT Personal, a tumor-informed liquid biopsy test for detection of minimal residual disease (MRD), therapy response and recurr... The company belongs to the Sundhed sector, more specifically the Diagnostics & Research industry, is headquartered in USA, and is traded on the USA Stocks. See the key figures, earnings history and price development above to evaluate Personalis as an investment.
Did Personalis raise or lower its guidance?
Over the last 60 days we have not registered a guidance raise or cut from Personalis. The company can still adjust its guidance at quarterly reports or between reports — see the earnings history and the news overview above.
Is Personalis making money or losing money?
No, Personalis is currently not making money — the company is losing money with a negative profit margin of -148.1%, a substantial loss. That means the business loses money on every dollar of revenue. For growth stocks investing in expansion this is normal — but it raises the risk if the company does not reach break-even before its capital runs out.
Can Personalis go bankrupt?
The bankruptcy risk of Personalis is rated as elevated. Altman Z2 (a model for assessing financial distress) is -0.39 — that places the company in the weak zone. This is a probability based on the numbers, not a verdict — bankruptcy is not imminent. But the balance sheet is measurably weaker than average, so watch the debt, liquidity and possible capital raises. The Piotroski score (financial health 0-9, higher is better) is 1 — which is weak. Debt relative to equity is 33% (low). Remember: models like Altman Z2 are statistical — unexpected shocks (fraud, a sector collapse, lawsuits) can always happen. Spread your portfolio.
Does Personalis have a lot of debt?
No, Personalis has low debt relative to equity. The debt-to-equity ratio (D/E — interest-bearing debt to equity) is 33%. For the sundhed sector, anything below 80% counts as low debt. Note: D/E levels are highly sector-specific — a bank at 300% debt is normal, a tech stock at 300% is extremely leveraged. Always compare with similar companies in the same sector.