Iovance Biotherapeutics (IOVA.US) Price Target 2026/2027: 40% Upside – Rating and Stock Analysis

5,88
35,48%
Price history for Iovance Biotherapeutics (IOVA.US) – stock price at 5.88 $, August 2026
Iovance Biotherapeutics stock price – price development 2026. Updated Aug 6, 2026.
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Iovance Biotherapeutics Price Target 2026: Analysts See 40% Upside

The average price target for Iovance Biotherapeutics is $8.22. This price target represents the analysts' view of the stock price over the next 12 months. The stock may be undervalued, because the price target is higher than the current price. The stock is 39,80% below the target, which can point to potential returns within the next 12 months if the analysts' view proves right. Also consider the stock's valuation ratios such as P/E, P/S and P/B, plus the technical analysis further down the page, for the full picture.

Is Iovance Biotherapeutics overvalued or undervalued?

Iovance Biotherapeutics is currently undervalued with a gap of 39.8% relative to the price target.


The current price is $5.88, which places Iovance Biotherapeutics in the undervalued category. The stock is considered undervalued when the price is below $7.40, and overvalued when the price exceeds $9.04.


The fair value range is defined as ±10% of the price target, because price targets are estimates rather than exact values. For Iovance Biotherapeutics, the fair value range lies between $7.40 and $9.04.


See the full price target analysis for Iovance Biotherapeutics →

Analyst Ratings for Iovance Biotherapeutics stock in 2026: Buy

12 analysts cover Iovance Biotherapeutics. The majority is positive, with 66.7% recommending Buy, while 33.3% recommend Hold. The average price target is $8.22, which gives an upside of 39.8% from the current price.

Consensus: Buy (4.08/5)
Strong Buy
5 (41.7%)
Buy
3 (25%)
Hold
4 (33.3%)
Strong Sell Sell Hold Buy Strong Buy
4.08 out of 5 based on 12 analysts

About Iovance Biotherapeutics – Bioteknologi

Iovance Biotherapeutics, Inc., a commercial-stage biopharmaceutical company, develops and commercializes cell therapies using autologous tumor infiltrating lymphocyte for the treatment of metastatic melanoma and other solid tumor cancers in the United States and internationally. The company offers Amtagvi, an individualized T cell therapy for solid tumor cancer and for the treatment of adult patients with previously treated advanced, or unresectable or metastatic melanomal; and Proleukin, an interleukin-2 product for the treatment of patients with metastatic melanoma and metastatic renal cell carcinoma. It also develops lifileucel for the treatment of melanoma, cervical cancer, non-small cell lung cancer (NSCLC), endometrial cancer, and head and neck squamous cell carcinoma (HNSCC); LN-145-S1 to treat melanoma and HNSCC; LN-145 Gen 3 and core biopsy for the treatment of NSCLC; LN-145 Gen 3 to treat melanoma and HNSCC; IOV-2001 to treat chronic lymphocytic leukemia and small lymphocytic lymphoma; IOV-4001 for the treatment of melanoma and NSCLC; and IOV-3001 for use in the TIL therapy treatment regimen. The company has collaborations and licensing agreements with National Institutes of Health; the National Cancer Institute; Cellectis S.A.; Novartis Pharma AG; and Boehringer Ingelheim Biopharmaceuticals GmbH. The company was formerly known as Lion Biotechnologies, Inc. and changed its name to Iovance Biotherapeutics, Inc. in June 2017. Iovance Biotherapeutics, Inc. was incorporated in 2007 and is headquartered in San Carlos, California. Read more about the company

Key Figures for Iovance Biotherapeutics

$ 1,9B Market cap
$ 286M Revenue
Bioteknologi Industry
- P/E
6.82 P/S
2.52 P/B
USA Listed on exchange
Sundhed Sector

What kind of stock is Iovance Biotherapeutics?

Momentum stock

Iovance Biotherapeutics is classified as a momentum stock with a momentum score in the top 27% of all stocks. The price has risen 0.0% over the long term.

Score Overview for Iovance Biotherapeutics

💰 Value Score 21/100 (Low)
⭐ Quality Score 3/100 (Very Low)
🚀 Momentum Score 73/100 (High)
📊 Total Score 32/100

⚠️ 5 red flags identified 4 critical

Our analysis has identified 5 potential risk factors in Iovance Biotherapeutics that investors should be aware of.

⚠️ Weak financial health: The Piotroski score is only 3/9 – the company shows signs of weakened profitability, liquidity or capital structure.
🚨 Weak balance sheet (elevated risk): Altman Z2 is -6.52 – the balance sheet is measurably weaker than average. This is a risk signal based on the numbers, not a bankruptcy prediction.
🚨 Negative profit margin: The profit margin is -123.9% – the company is losing money on its operations.
🚨 Negative return on equity: ROE is -47.5% – the company is generating a negative return for shareholders.
🚨 High short interest: 24.0% of the shares are sold short – many professional investors are betting on price declines.

📈 Valuation

The P/S ratio is 6.8 (high — the market pays a premium for the revenue). The P/B ratio is 2.5.

🏦 Financial Health

The Piotroski score is 3 out of 9 — weak financial health, be careful. Altman Z2 is -6.52 (weak balance sheet — elevated risk). The debt-to-equity ratio (D/E) is 28.2% — low debt, a solid balance sheet.

🚀 Momentum & Short Interest

Short interest is 23.95% — very high, the market is skeptical.

Insider Trading in Iovance Biotherapeutics 2026: The Signal Is negative

In 2026, insiders at Iovance Biotherapeutics have made 20 transactions, all of which were sales. On a net basis, insiders took 2,110,891 $ out of the stock. Active insiders include Vogt Frederick G, Puri Raj K., GRAF FINCKENSTEIN FRIEDRICH and others. In the short term (last 3 months), the insider signal is negative.

Short-Term Signal (3 months): Negative

Insiders have exclusively sold shares over the last 3 months.

Over the last 3 months: 0 purchases and 9 sales. A net 466,781 $ out of the stock.

Long-Term Signal (all transactions): Negative

Insiders have exclusively sold shares in the recent period. This can suggest management sees limited opportunity.

Across the last 20 transactions: 0 purchases and 20 sales. A net 2,110,891 $ out of the stock.

Latest sale: Vogt Frederick G sold 15,625 shares at 4 $ each on 2026-06-05.

Who is selling: Vogt Frederick G, Puri Raj K., GRAF FINCKENSTEIN FRIEDRICH, BILINSKY IGOR, Kirby Daniel Gordon.

Latest Insider Trades in Iovance Biotherapeutics (2026)

The table shows the last 20 reported insider transactions in Iovance Biotherapeutics. Green rows are purchases, red rows are sales. The data is based on official filings.

Transaction date Name Type Number of shares Price per share ($) Total amount ($)
2026-06-05 Vogt Frederick G Sell 15,625 4 66,094
2026-06-05 Puri Raj K. Sell 9,766 4 41,310
2026-06-05 GRAF FINCKENSTEIN FRIEDRICH Sell 7,813 4 33,049
2026-06-05 BILINSKY IGOR Sell 7,813 4 33,049
2026-06-01 Vogt Frederick G Sell 41,668 4 165,005
2026-06-01 Puri Raj K. Sell 5,469 4 21,657
2026-06-01 GRAF FINCKENSTEIN FRIEDRICH Sell 8,790 4 34,808
2026-06-01 BILINSKY IGOR Sell 8,790 4 34,808
2026-05-11 Kirby Daniel Gordon Sell 10,000 4 37,000
2026-03-05 Vogt Frederick G Sell 62,493 5 286,218

Who is buying and selling Iovance Biotherapeutics shares in 2026?

The following insiders have sold shares: Vogt Frederick G, Puri Raj K., GRAF FINCKENSTEIN FRIEDRICH, BILINSKY IGOR, Kirby Daniel Gordon. In total, 2,110,891 $ was sold across 20 transactions. Insider trades are legal transactions in which executives and board members buy or sell shares of their own company. These transactions are reported to the SEC and are publicly available.

Iovance Biotherapeutics Short Selling 2026: 24.0% Sold Short

Extremely shorted: 24.0% of the free float
Short % of free float
24.0%
Assessment
Extremely shorted
Short squeeze risk
Very High
Data source
SEC
Updated daily
The stock has an extremely high share of short selling. More than 20% of the freely traded shares are sold short, which is unusual and can point to great skepticism among institutional investors. The risk of a short squeeze on positive news is considerable.

What does this mean for you as an investor?
A short interest of 24.0% means that 24.0% of the freely traded shares in Iovance Biotherapeutics have been borrowed and sold by investors betting on falling prices. On positive surprises (e.g. a strong earnings report), short sellers can be forced to buy back shares quickly to close their positions, which can cause a short squeeze with sharp price gains in a short time.

The next potential catalyst is the earnings report on 8/6/2026. With a short interest of 24.0%, the report can trigger considerable volatility.

Data is updated daily based on official filings with the SEC.
Short Interest Scale
0% 2% 5% 10% 20%+
Low Moderate High Very High Extreme
24.0%

Iovance Biotherapeutics Earnings – ⚡ Reporting TODAY 8/6/2026

The next earnings date for Iovance Biotherapeutics is not yet available. Check the company's investor calendar for more information.



Technical Analysis of Iovance Biotherapeutics 2026 – Signal: Strong Buy

Overall Technical Signal: Strong Buy

Based on trend analysis (SMA50/SMA200) and MACD trend (positive/negative on a daily + weekly basis). Updated August 6, 2026.

Technical analysis of Iovance Biotherapeutics (IOVA.US) – RSI 47, MACD positive (bullish), daily candlestick chart August 2026
Iovance Biotherapeutics technical analysis – candlestick chart with RSI and MACD. Updated Aug 6, 2026.

Trend Analysis of Iovance Biotherapeutics, Inc

Iovance Biotherapeutics, Inc is in a short-term downtrend. The price of $4.34 is 6.4% below the 20-day average ($4.64). Medium term, the picture is positive: the price is 0.4% above the 50-day average ($4.32). Long term, the stock is 30.3% above the 200-day average ($3.33), which confirms a long-term uptrend.

Golden Cross: The 50-day average (4.32) is above the 200-day average (3.33), which is a classic bullish signal for Iovance Biotherapeutics, Inc.

Is Iovance Biotherapeutics, Inc overbought or oversold?

Iovance Biotherapeutics, Inc has an RSI of 46.8, right in the middle of the neutral zone. There is no clear buying or selling pressure.

MACD Analysis for Iovance Biotherapeutics, Inc

Daily MACD: MACD is positive (0.029), which means the short-term trend is bullish (the 12-day EMA is above the 26-day EMA). MACD is below the signal line (0.124) by 0.095, which suggests the positive momentum is fading – the trend could be turning.

Weekly MACD: MACD5 is positive (0.389), which indicates a broader bullish long-term trend. MACD5 is above the signal line (0.338) by 0.051, which confirms rising long-term momentum.

Overall MACD assessment: Both the daily and weekly trend are bullish (MACD positive). However, momentum shows signs of weakening on a daily basis. Watch whether the trend holds.

Risk Profile for Iovance Biotherapeutics, Inc

Iovance Biotherapeutics, Inc has an annual standard deviation of 93.6%, which classifies the stock as extreme risk. Only risk-tolerant investors should consider this stock, because the price swings can be very large.

Overall Technical Conclusion for Iovance Biotherapeutics, Inc

Trend: Positive. The price trades above SMA50 and SMA200.

MACD trend (zero line): Daily bullish (0.029). Weekly bullish (0.389).

MACD momentum (signal): Daily falling. Weekly rising.

RSI: 46.8 – neutral.

Technical signal: Strong Buy

The price is in an uptrend (above SMA50/SMA200) and MACD is positive on both a daily and weekly basis. Trend and MACD trend confirm each other – the strongest technical buy signal.

Frequently Asked Questions About Iovance Biotherapeutics stock in 2026

Should you buy Iovance Biotherapeutics stock now?
Yes, the technical signal for Iovance Biotherapeutics is currently BUY. Iovance Biotherapeutics trades at $5.88 as of 8/6/2026. The overall technical signal is: Strong Buy. The technical analysis shows the following: MACD is positive (bullish trend) at 0.029 with falling momentum (signal: 0.124); RSI is at 46.8 (neutral zone); the stock is in a short-term uptrend (price above the 20-day average); the analyst price target of $8.22 points to 39.8% upside. The stock is in a broader uptrend (above SMA50/SMA200). This is a technical observation based on current data, not investment advice.
What is the price target for Iovance Biotherapeutics stock?
The average analyst price target for Iovance Biotherapeutics is $8.22. The current price is $5.88, which gives an upside of 39.8%. Based on this, the stock is considered undervalued. The fair value range (±10% of the price target) is between $7.40 and $9.04.
Is Iovance Biotherapeutics a dividend stock?
No, Iovance Biotherapeutics does not currently pay a dividend to shareholders. The company reinvests its profits in growth instead of paying dividends.
What is the risk of Iovance Biotherapeutics stock?
Iovance Biotherapeutics is rated as a stock with extreme risk. the annual standard deviation is 93.6%, which classifies the stock as extreme risk.
Is Iovance Biotherapeutics overvalued?
No, Iovance Biotherapeutics is considered undervalued based on the analyst price target (39.8% upside). Iovance Biotherapeutics has the following valuation ratios: a P/S ratio of 6.8, a P/B ratio of 2.5. The analyst price target suggests that the stock is undervalued by 39.8%.
Is Iovance Biotherapeutics overbought?
No, Iovance Biotherapeutics is not overbought. RSI is at 46.8 (neutral zone). The technical indicators show: RSI is at 46.8 (neutral zone between 30-70), which signals neither overbought nor oversold. In addition, the price is 26.9% above the 20-day average (short-term uptrend). In addition, MACD is positive, but momentum is falling.
When is the next Iovance Biotherapeutics earnings report?
Iovance Biotherapeutics reports earnings TODAY, August 6, 2026! The stock currently trades at $5.88. Watch how the price reacts after the release.
Is Iovance Biotherapeutics shorted?
Yes, Iovance Biotherapeutics is shorted with 24.0% of the free float sold short. This is an extremely high level of short selling, which points to great skepticism among institutional investors. The risk of a short squeeze on positive news or earnings is very high. Data is updated daily based on official filings with the SEC.
Are insiders buying Iovance Biotherapeutics stock?
No, insiders are not buying Iovance Biotherapeutics shares – they are net sellers. Over the last 3 months, insiders have made 0 purchases and 9 sales. On a net basis, 466,781 $ worth of shares were sold. Across the last 20 reported transactions, the split is 0 purchases and 20 sales, with a net 2,110,891 $ sold. Active sellers include Vogt Frederick G, Puri Raj K., GRAF FINCKENSTEIN FRIEDRICH and others. Insider selling can have several explanations (e.g. planned 10b5-1 sales, portfolio diversification or taxes), but sustained selling by several insiders is worth watching closely.
Is Iovance Biotherapeutics a good stock?
Based on our total score, Iovance Biotherapeutics is rated as a poor stock with a total score of 32 out of 100. The stock scores below average on value, quality and momentum – it sits at the lower end of the market. The score is made up of Value: 21/100, Quality: 3/100, Momentum: 73/100. In addition: analysts see 39.8% upside to the price target; technical signal: Strong Buy. Whether Iovance Biotherapeutics is a good investment depends on your time horizon, risk profile and portfolio. This is a data-driven observation, not investment advice.
What is the outlook for Iovance Biotherapeutics stock?
The outlook for Iovance Biotherapeutics based on current data: the average analyst price target is $8.22 (+39.8%); the stock is in an uptrend (above SMA50 and SMA200); the next earnings report is due on 8/6/2026, which can move the price. Keep in mind that stock prices are affected by many factors, including earnings reports, the economy and market sentiment. Past returns are no guarantee of future returns.
Why is Iovance Biotherapeutics stock rising?
Iovance Biotherapeutics is rising right now. The technical indicators show: the price is 26.9% above the 20-day average; short interest is 24.0% (high – many are betting on a decline); insiders have mostly been selling the stock recently. For the latest context, see our technical analysis, insider section and news overview above.
How high can Iovance Biotherapeutics go?
The average analyst price target for Iovance Biotherapeutics is $8.22, which corresponds to a potential gain of 39.8% from the current price of $5.88. Keep in mind that price targets are estimates, not guarantees. Actual price moves depend on earnings, market conditions and unexpected events.
How low can Iovance Biotherapeutics fall?
We lack enough history to give a specific floor for Iovance Biotherapeutics. Remember: past price swings are no guarantee for the future — a stock can fall further than the last 52 weeks suggest, especially on profit warnings, sector crises or a market crash. Use stop-loss orders and spread your portfolio to limit losses in single stocks.
What does Iovance Biotherapeutics do?
Iovance Biotherapeutics, Inc., a commercial-stage biopharmaceutical company, develops and commercializes cell therapies using autologous tumor infiltrating lymphocyte for the treatment of metastatic melanoma and other solid tumor cancers in the United States and internationall... The company belongs to the Sundhed sector, more specifically the Bioteknologi industry, is headquartered in USA, and is traded on the USA Stocks. See the key figures, earnings history and price development above to evaluate Iovance Biotherapeutics as an investment.
Did Iovance Biotherapeutics raise or lower its guidance?
Over the last 60 days we have not registered a guidance raise or cut from Iovance Biotherapeutics. The company can still adjust its guidance at quarterly reports or between reports — see the earnings history and the news overview above.
Is Iovance Biotherapeutics making money or losing money?
No, Iovance Biotherapeutics is currently not making money — the company is losing money with a negative profit margin of -123.9%, a substantial loss. That means the business loses money on every dollar of revenue. For growth stocks investing in expansion this is normal — but it raises the risk if the company does not reach break-even before its capital runs out.
Can Iovance Biotherapeutics go bankrupt?
The bankruptcy risk of Iovance Biotherapeutics is rated as elevated. Altman Z2 (a model for assessing financial distress) is -6.52 — that places the company in the weak zone. This is a probability based on the numbers, not a verdict — bankruptcy is not imminent. But the balance sheet is measurably weaker than average, so watch the debt, liquidity and possible capital raises. The Piotroski score (financial health 0-9, higher is better) is 3 — which is weak. Debt relative to equity is 28% (low). Remember: models like Altman Z2 are statistical — unexpected shocks (fraud, a sector collapse, lawsuits) can always happen. Spread your portfolio.
Does Iovance Biotherapeutics have a lot of debt?
No, Iovance Biotherapeutics has low debt relative to equity. The debt-to-equity ratio (D/E — interest-bearing debt to equity) is 28%. For the sundhed sector, anything below 80% counts as low debt. Note: D/E levels are highly sector-specific — a bank at 300% debt is normal, a tech stock at 300% is extremely leveraged. Always compare with similar companies in the same sector.