Heron Therapeutics (HRTX.US) Price Target and Rating 2026/2027

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Heron Therapeutics 2026 Price Target

The average price target for Heron Therapeutics is $7.00. This price target represents the analysts' view of the stock price over the next 12 months. The stock may be undervalued, because the price target is higher than the current price. The stock is 0% below the target, which can point to potential returns within the next 12 months if the analysts' view proves right. Also consider the stock's valuation ratios such as P/E, P/S and P/B, plus the technical analysis further down the page, for the full picture.

Is Heron Therapeutics overvalued or undervalued?

Heron Therapeutics is currently fairly valued with a gap of 0% relative to the price target.


The current price is $0.00, which places Heron Therapeutics in the fairly valued category. The stock is considered undervalued when the price is below $6.30, and overvalued when the price exceeds $7.70.


The fair value range is defined as ±10% of the price target, because price targets are estimates rather than exact values. For Heron Therapeutics, the fair value range lies between $6.30 and $7.70.


See the full price target analysis for Heron Therapeutics →

Analyst Ratings for Heron Therapeutics stock in 2026: Strong Buy

3 analysts cover Heron Therapeutics. There is broad agreement on a positive view — 100% recommend buying.

Consensus: Strong Buy (4.67/5)
Strong Buy
2 (66.7%)
Buy
1 (33.3%)
Strong Sell Sell Hold Buy Strong Buy
4.67 out of 5 based on 3 analysts

About Heron Therapeutics – Bioteknologi

Heron Therapeutics, Inc., a commercial-stage biotechnology company, engages in developing and commercializing therapeutic that enhances medical care. The company's product candidates utilize its proprietary Biochronomer, a drug delivery technology, which delivers therapeutic levels of a range of short-acting pharmacological agents over a period from days to weeks with a single administration. It offers SUSTOL (granisetron), an extended-release injection for the prevention of acute and delayed nausea and vomiting associated with moderately emetogenic chemotherapy, or anthracycline and cyclophosphamide combination chemotherapy regimens; and CINVANTI, an intravenous formulation of aprepitant, a substance P/neurokinin-1 receptor antagonist for the prevention of acute and delayed nausea and vomiting associated with highly emetogenic cancer chemotherapy, as well as nausea and vomiting associated with moderately emetogenic cancer chemotherapy. The company is also developing ZYNRELEF, a dual-acting local anesthetic that delivers a fixed-dose combination of the local anesthetic bupivacaine and a low dose of the nonsteroidal anti-inflammatory drug meloxicam; and APONVIE, an intravenous formulation of a substance P/neurokinin-1 receptor antagonist indicated for the prevention of postoperative nausea and vomiting in adults. Heron Therapeutics, Inc. was formerly known as A.P. Pharma, Inc. and changed its name to Heron Therapeutics, Inc. in January 2014. The company was founded in 1983 and is headquartered in Cary, North Carolina. Read more about the company

Key Figures for Heron Therapeutics

$ 59.3M Market cap
$ 151M Revenue
Bioteknologi Industry
- P/E
0.39 P/S
10.47 P/B
USA Listed on exchange

What kind of stock is Heron Therapeutics?

Speculative stock

Heron Therapeutics is classified as a speculative stock.

Score Overview for Heron Therapeutics

💰 Value Score 30/100 (Low)
⭐ Quality Score 10/100 (Very Low)
🚀 Momentum Score 2/100 (Very Low)
📊 Total Score 14/100

⚠️ 6 red flags identified 5 critical

Our analysis has identified 6 potential risk factors in Heron Therapeutics that investors should be aware of.

🚨 High debt: The debt-to-equity ratio is 1,000% – the company carries considerably more debt than equity, which raises the financial risk.
⚠️ Weak financial health: The Piotroski score is only 2/9 – the company shows signs of weakened profitability, liquidity or capital structure.
🚨 Weak balance sheet (elevated risk): Altman Z2 is -22.35 – the balance sheet is measurably weaker than average. This is a risk signal based on the numbers, not a bankruptcy prediction.
🚨 Negative profit margin: The profit margin is -22.5% – the company is losing money on its operations.
🚨 Negative return on equity: ROE is -2,408.9% – the company is generating a negative return for shareholders.
🚨 High short interest: 31.4% of the shares are sold short – many professional investors are betting on price declines.

📈 Valuation

The P/S ratio is 0.4 (low — potentially undervalued relative to revenue). The P/B ratio is 10.5.

🏦 Financial Health

The Piotroski score is 2 out of 9 — weak financial health, be careful. Altman Z2 is -22.35 (weak balance sheet — elevated risk). The debt-to-equity ratio (D/E) is 1,000.0% — high debt, which raises the risk.

🚀 Momentum & Short Interest

Short interest is 31.36% — very high, the market is skeptical.

Insider Trading in Heron Therapeutics 2026: The Signal Is negative

In 2026, insiders at Heron Therapeutics have made 20 transactions – split into 7 purchases and 13 sales. On a net basis, insiders put 9,799,707 $ into the stock, which is a positive signal. Active insiders include Rubric Capital Management LP, Morgan Adam, Forbes William P and others. In the short term (last 3 months), the insider signal is negative.

Short-Term Signal (3 months): Negative

Insiders have exclusively sold shares over the last 3 months.

Over the last 3 months: 0 purchases and 8 sales. A net 48,363 $ out of the stock.

Long-Term Signal (all transactions): Mostly positive

Insiders have bought considerably more than they have sold. This suggests several key people see value in the stock.

Across the last 20 transactions: 7 purchases and 13 sales. A net 9,799,707 $ into the stock.

Latest purchase: Rubric Capital Management LP bought 2,387,225 shares at 2 $ each on 2025-08-08. The stock has since fallen 77.9%.

Latest sale: Hensley Mark Earl sold 31,250 shares at 1 $ each on 2026-08-06.

Who is buying: Rubric Capital Management LP, Morgan Adam, Forbes William P, Duarte Ira, Collard Craig A.

Who is selling: Hensley Mark Earl, Forbes William P, Duarte Ira, Peraza Lisa, Collard Craig A.

Latest Insider Trades in Heron Therapeutics (2026)

The table shows the last 20 reported insider transactions in Heron Therapeutics. Green rows are purchases, red rows are sales. The data is based on official filings.

Transaction date Name Type Number of shares Price per share ($) Total amount ($)
2026-08-06 Hensley Mark Earl Sell 31,250 1 15,625
2026-07-31 Forbes William P Sell 11,694 1 5,847
2026-07-31 Duarte Ira Sell 11,694 1 5,847
2026-07-30 Forbes William P Sell 11,769 1 5,885
2026-07-30 Duarte Ira Sell 13,535 1 6,768
2026-07-19 Forbes William P Sell 3,874 0 1,821
2026-07-19 Duarte Ira Sell 3,874 0 1,821
2026-06-16 Duarte Ira Sell 12,500 0 4,750
2025-08-08 Rubric Capital Management LP Buy 2,387,225 2 3,580,838
2025-08-08 Morgan Adam Buy 1,766,546 2 2,649,819

Who is buying and selling Heron Therapeutics shares in 2026?

The following insiders have bought shares in Heron Therapeutics: Rubric Capital Management LP, Morgan Adam, Forbes William P, Duarte Ira, Collard Craig A. In total, 9,925,396 $ was bought across 7 transactions. The following insiders have sold shares: Hensley Mark Earl, Forbes William P, Duarte Ira, Peraza Lisa, Collard Craig A. In total, 125,689 $ was sold across 13 transactions. Insider trades are legal transactions in which executives and board members buy or sell shares of their own company. These transactions are reported to the SEC and are publicly available.

Heron Therapeutics Short Selling 2026: 31.4% Sold Short

Extremely shorted: 31.4% of the free float
Short % of free float
31.4%
Assessment
Extremely shorted
Short squeeze risk
Very High
Data source
SEC
Updated daily
The stock has an extremely high share of short selling. More than 20% of the freely traded shares are sold short, which is unusual and can point to great skepticism among institutional investors. The risk of a short squeeze on positive news is considerable.

What does this mean for you as an investor?
A short interest of 31.4% means that 31.4% of the freely traded shares in Heron Therapeutics have been borrowed and sold by investors betting on falling prices. On positive surprises (e.g. a strong earnings report), short sellers can be forced to buy back shares quickly to close their positions, which can cause a short squeeze with sharp price gains in a short time.

Data is updated daily based on official filings with the SEC.
Short Interest Scale
0% 2% 5% 10% 20%+
Low Moderate High Very High Extreme
31.4%

When Does Heron Therapeutics Report Earnings?

The next earnings date for Heron Therapeutics is not yet available. Check the company's investor calendar for more information.



Technical Analysis of Heron Therapeutics 2026 – Signal: Sell

Overall Technical Signal: Sell

Based on trend analysis (SMA50/SMA200) and MACD trend (positive/negative on a daily + weekly basis). Updated August 28, 2026.

Trend Analysis of Heron Therapeutics, Inc

Heron Therapeutics, Inc is in a short-term downtrend. The price of $0.33 is 11.9% below the 20-day average ($0.38). Medium term, the picture is negative: the price is 20.4% below the 50-day average ($0.42). Long term, the stock is 63.5% below the 200-day average ($0.91), which signals a long-term downtrend.

Death Cross: The 50-day average (0.42) is below the 200-day average (0.91), which is a classic bearish signal for Heron Therapeutics, Inc.

Is Heron Therapeutics, Inc overbought or oversold?

Heron Therapeutics, Inc has an RSI of 37.3. The stock sits in the lower part of the neutral zone, which points to weak momentum without being oversold.

MACD Analysis for Heron Therapeutics, Inc

Daily MACD: MACD is negative (-0.040), which means the short-term trend is bearish (the 12-day EMA is below the 26-day EMA). MACD is below the signal line (-0.040) by 0.000, which confirms growing negative momentum in the downtrend.

Weekly MACD: MACD5 is negative (-0.205), which indicates a broader bearish long-term trend. MACD5 is below the signal line (-0.198) by 0.007, which confirms continued negative long-term momentum.

Overall MACD assessment: Both the daily and weekly MACD are negative and below their signal lines. Trend and momentum are negative across time horizons – the strongest bearish signal.

Risk Profile for Heron Therapeutics, Inc

Heron Therapeutics, Inc has an annual standard deviation of 84.6%, which classifies the stock as Extremely speculative. Only risk-tolerant investors should consider this stock, because the price swings can be very large.

Overall Technical Conclusion for Heron Therapeutics, Inc

Trend: Neutral/mixed.

MACD trend (zero line): Daily bearish (-0.040). Weekly bearish (-0.205).

MACD momentum (signal): Daily falling. Weekly falling.

RSI: 37.3 – neutral.

Technical signal: Sell

The trend is negative and MACD is below the zero line, which confirms the bearish momentum. Consider reducing the position or setting a stop-loss.

Frequently Asked Questions About Heron Therapeutics stock in 2026

Should you buy Heron Therapeutics stock now?
No, the technical signal for Heron Therapeutics is currently SELL. Heron Therapeutics trades at $0.00 as of 8/28/2026. The overall technical signal is: Sell. The technical analysis shows the following: MACD is negative (bearish trend) at -0.040 with falling momentum (signal: -0.040); RSI is at 37.3 (neutral zone). This is a technical observation based on current data, not investment advice.
What is the price target for Heron Therapeutics stock?
There is currently no active analyst price target for Heron Therapeutics.
Is Heron Therapeutics a dividend stock?
No, Heron Therapeutics does not currently pay a dividend to shareholders. The company reinvests its profits in growth instead of paying dividends.
What is the risk of Heron Therapeutics stock?
Heron Therapeutics is rated as a stock in the risk category Extremely speculative. the annual standard deviation is 84.6%, which classifies the stock as Extremely speculative.
Is Heron Therapeutics overvalued?
Heron Therapeutics has the following valuation ratios: a P/S ratio of 0.4, a P/B ratio of 10.5.
Is Heron Therapeutics overbought?
No, Heron Therapeutics is not overbought. RSI is at 37.3 (neutral zone). The technical indicators show: RSI is at 37.3 (neutral zone between 30-70), which signals neither overbought nor oversold. In addition, MACD is negative with falling momentum (bearish).
When is the next Heron Therapeutics earnings report?
The date of the next earnings report for Heron Therapeutics has not been published yet. Check the company's investor calendar for updates.
Is Heron Therapeutics shorted?
Yes, Heron Therapeutics is shorted with 31.4% of the free float sold short. This is an extremely high level of short selling, which points to great skepticism among institutional investors. The risk of a short squeeze on positive news or earnings is very high. Data is updated daily based on official filings with the SEC.
Are insiders buying Heron Therapeutics stock?
No, insiders are not buying Heron Therapeutics shares – they are net sellers. Over the last 3 months, insiders have made 0 purchases and 8 sales. On a net basis, 48,363 $ worth of shares were sold. Across the last 20 reported transactions, the split is 7 purchases and 13 sales, with a net 9,799,707 $ bought. Active sellers include Hensley Mark Earl, Forbes William P, Duarte Ira and others. Insider selling can have several explanations (e.g. planned 10b5-1 sales, portfolio diversification or taxes), but sustained selling by several insiders is worth watching closely.
Is Heron Therapeutics a good stock?
Based on our total score, Heron Therapeutics is rated as a disastrous stock with a total score of 14 out of 100. The stock scores very low on value, quality and momentum – it is among the worst in our database. The score is made up of Value: 30/100, Quality: 10/100, Momentum: 2/100. In addition: technical signal: Sell. Whether Heron Therapeutics is a good investment depends on your time horizon, risk profile and portfolio. This is a data-driven observation, not investment advice.
What is the outlook for Heron Therapeutics stock?
The outlook for Heron Therapeutics based on current data: Detailed data is currently not available. Keep in mind that stock prices are affected by many factors, including earnings reports, the economy and market sentiment. Past returns are no guarantee of future returns.
Why is Heron Therapeutics stock moving?
Heron Therapeutics is moving right now. The technical indicators show: short interest is 31.4% (high – many are betting on a decline); insiders have mostly been selling the stock recently. For the latest context, see our technical analysis, insider section and news overview above.
How high can Heron Therapeutics go?
There is currently no active analyst price target for Heron Therapeutics. Keep in mind that price targets are estimates, not guarantees. Actual price moves depend on earnings, market conditions and unexpected events.
How low can Heron Therapeutics fall?
We lack enough history to give a specific floor for Heron Therapeutics. Remember: past price swings are no guarantee for the future — a stock can fall further than the last 52 weeks suggest, especially on profit warnings, sector crises or a market crash. Use stop-loss orders and spread your portfolio to limit losses in single stocks.
What does Heron Therapeutics do?
Heron Therapeutics, Inc., a commercial-stage biotechnology company, engages in developing and commercializing therapeutic that enhances medical care. The company's product candidates utilize its proprietary Biochronomer, a drug delivery technology, which delivers therapeutic l... The company belongs to the Healthcare sector, more specifically the Bioteknologi industry, is headquartered in USA, and is traded on the USA Stocks. See the key figures, earnings history and price development above to evaluate Heron Therapeutics as an investment.
Did Heron Therapeutics raise or lower its guidance?
Over the last 60 days we have not registered a guidance raise or cut from Heron Therapeutics. The company can still adjust its guidance at quarterly reports or between reports — see the earnings history and the news overview above.
Is Heron Therapeutics making money or losing money?
No, Heron Therapeutics is currently not making money — the company is losing money with a negative profit margin of -22.5%, a substantial loss. That means the business loses money on every dollar of revenue. For growth stocks investing in expansion this is normal — but it raises the risk if the company does not reach break-even before its capital runs out.
Can Heron Therapeutics go bankrupt?
The bankruptcy risk of Heron Therapeutics is rated as elevated. Altman Z2 (a model for assessing financial distress) is -22.35 — that places the company in the weak zone. This is a probability based on the numbers, not a verdict — bankruptcy is not imminent. But the balance sheet is measurably weaker than average, so watch the debt, liquidity and possible capital raises. The Piotroski score (financial health 0-9, higher is better) is 2 — which is weak. Debt relative to equity is 1,000% (high). Remember: models like Altman Z2 are statistical — unexpected shocks (fraud, a sector collapse, lawsuits) can always happen. Spread your portfolio.
Does Heron Therapeutics have a lot of debt?
Yes, Heron Therapeutics has elevated debt relative to equity. The debt-to-equity ratio (D/E — interest-bearing debt to equity) is 1,000%. For the healthcare sector, anything above 150% counts as elevated — that raises the financial risk, especially if interest rates rise or earnings fall. In healthcare, 80-150% is typical — large pharma companies carry debt for research and acquisitions. Note: D/E levels are highly sector-specific — a bank at 300% debt is normal, a tech stock at 300% is extremely leveraged. Always compare with similar companies in the same sector.