Ascendis Pharma (ASND.US) Price Target and Rating 2026/2027

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Ascendis Pharma 2026 Price Target

The average price target for Ascendis Pharma is $314.62. This price target represents the analysts' view of the stock price over the next 12 months. The stock may be undervalued, because the price target is higher than the current price. The stock is 0% below the target, which can point to potential returns within the next 12 months if the analysts' view proves right. Also consider the stock's valuation ratios such as P/E, P/S and P/B, plus the technical analysis further down the page, for the full picture.

Is Ascendis Pharma overvalued or undervalued?

Ascendis Pharma is currently fairly valued with a gap of 0% relative to the price target.


The current price is $0.00, which places Ascendis Pharma in the fairly valued category. The stock is considered undervalued when the price is below $283.16, and overvalued when the price exceeds $346.08.


The fair value range is defined as ±10% of the price target, because price targets are estimates rather than exact values. For Ascendis Pharma, the fair value range lies between $283.16 and $346.08.


See the full price target analysis for Ascendis Pharma →

Analyst Ratings for Ascendis Pharma stock in 2026: Strong Buy

16 analysts cover Ascendis Pharma. There is broad agreement on a positive view — 100% recommend buying.

Consensus: Strong Buy (4.75/5)
Strong Buy
12 (75%)
Buy
4 (25%)
Strong Sell Sell Hold Buy Strong Buy
4.75 out of 5 based on 16 analysts

About Ascendis Pharma – Bioteknologi

Ascendis Pharma A/S, operates as a biopharmaceutical company that focuses on developing TransCon-based therapies for unmet medical needs in Europe, the United States, and internationally. The company offers SKYTROFA for treating pediatric patients with growth hormone deficiency; and YORVIPATH, a once-daily subcutaneous injection for the treatment of adults with chronic hypoparathyroidism. It is also developing a pipeline of three independent endocrinology rare disease product candidates in clinical development, as well as focuses on advancing oncology therapeutic candidates. The company was incorporated in 2006 and is based in Hellerup, Denmark. Read more about the company

Key Figures for Ascendis Pharma

$ 16.4B Market cap
$ 1.0B Revenue
Bioteknologi Industry
19.16 P/E
15.68 P/S
9.89 P/B
USA Listed on exchange

What kind of stock is Ascendis Pharma?

Quality stock

Ascendis Pharma is classified as a quality stock with a Piotroski score of 8/9 and a quality score in the top 2% of all stocks.

Score Overview for Ascendis Pharma

💰 Value Score 41/100 (Neutral)
⭐ Quality Score 98/100 (Very High)
🚀 Momentum Score 58/100 (Neutral)
📊 Total Score 65/100

⚠️ 1 red flag identified 1 critical

Our analysis has identified 1 potential risk factor in Ascendis Pharma that investors should be aware of.

🚨 High debt: The debt-to-equity ratio is 1,000% – the company carries considerably more debt than equity, which raises the financial risk.

📈 Valuation

Ascendis Pharma trades at a P/E ratio of 19.2, which is close to the market average. The forward P/E is 15.7 (18% lower), which suggests the market expects rising earnings. The P/S ratio is 15.7 (high — the market pays a premium for the revenue). The P/B ratio is 9.9.

💵 Profitability & Growth

Ascendis Pharma has a profit margin of 70.9% (excellent) and an operating margin of 65.0%. Return on equity (ROE) is 118.8% — excellent return on equity. Return on assets (ROA) is 9.6%.

🏦 Financial Health

The Piotroski score is 8 out of 9 — excellent financial health. Altman Z2 is 1.93 (middle zone — moderate). The debt-to-equity ratio (D/E) is 1,000.0% — high debt, which raises the risk.

🚀 Momentum & Short Interest

Short interest is 6.66% — elevated, some investors are betting on a decline.

Insider Trading in Ascendis Pharma 2026: The Signal Is clearly positive

In 2026, insiders at Ascendis Pharma have made 6 transactions – split into 5 purchases and 1 sales. On a net basis, insiders took 4,199,110 $ out of the stock. Active insiders include BIENAIME JEAN JACQUES, SMITH SCOTT THOMAS, JENSEN FLEMMING STEEN. In the short term (last 3 months), the insider signal is clearly positive.

Short-Term Signal (3 months): Clearly positive

Insiders have exclusively bought shares over the last 3 months. This is a strong signal of confidence in the company in the short term.

Over the last 3 months: 2 purchases and 0 sales. A net 293,501 $ into the stock.

Long-Term Signal (all transactions): Mostly negative

Insiders have sold considerably more than they have bought. At large companies this can be due to planned sales (10b5-1 plans) and is not necessarily a negative signal.

Across the last 6 transactions: 5 purchases and 1 sales. A net 4,199,110 $ out of the stock.

Latest purchase: BIENAIME JEAN JACQUES bought 1,100 shares at 247 $ each on 2026-08-14. The stock has since risen 1%.

Latest sale: JENSEN FLEMMING STEEN sold 19,460 shares at 238 $ each on 2026-05-11.

Who is buying: BIENAIME JEAN JACQUES, SMITH SCOTT THOMAS.

Who is selling: JENSEN FLEMMING STEEN.

Latest Insider Trades in Ascendis Pharma (2026)

The table shows the last 6 reported insider transactions in Ascendis Pharma. Green rows are purchases, red rows are sales. The data is based on official filings.

Transaction date Name Type Number of shares Price per share ($) Total amount ($)
2026-08-14 BIENAIME JEAN JACQUES Buy 1,100 247 271,601
2026-06-02 SMITH SCOTT THOMAS Buy 100 219 21,900
2026-05-29 SMITH SCOTT THOMAS Buy 250 223 55,830
2026-05-29 BIENAIME JEAN JACQUES Buy 200 224 44,700
2026-05-26 BIENAIME JEAN JACQUES Buy 200 239 47,874
2026-05-11 JENSEN FLEMMING STEEN Sell 19,460 238 4,641,015

Who is buying and selling Ascendis Pharma shares in 2026?

The following insiders have bought shares in Ascendis Pharma: BIENAIME JEAN JACQUES, SMITH SCOTT THOMAS. In total, 441,905 $ was bought across 5 transactions. The following insiders have sold shares: JENSEN FLEMMING STEEN. In total, 4,641,015 $ was sold across 1 transactions. Insider trades are legal transactions in which executives and board members buy or sell shares of their own company. These transactions are reported to the SEC and are publicly available.

Ascendis Pharma Short Selling 2026: 6.7% Sold Short

High short interest: 6.7% of the free float
Short % of free float
6.7%
Assessment
High short interest
Short squeeze risk
Moderate
Data source
SEC
Updated daily
The stock has a high share of short selling. Between 5-10% of the freely traded shares are sold short, which suggests some investors are betting on falling prices. Positive surprises can lead to a moderate short squeeze.

What does this mean for you as an investor?
A short interest of 6.7% means that 6.7% of the freely traded shares in Ascendis Pharma have been borrowed and sold by investors betting on falling prices.

Data is updated daily based on official filings with the SEC.
Short Interest Scale
0% 2% 5% 10% 20%+
Low Moderate High Very High Extreme
6.7%

When Does Ascendis Pharma Report Earnings?

The next earnings date for Ascendis Pharma is not yet available. Check the company's investor calendar for more information.



Technical Analysis of Ascendis Pharma 2026 – Signal: Hold

Overall Technical Signal: Hold

Based on trend analysis (SMA50/SMA200) and MACD trend (positive/negative on a daily + weekly basis). Updated August 28, 2026.

Trend Analysis of Ascendis Pharma A/S

Ascendis Pharma A/S is in a short-term downtrend. The price of $249.36 is 0.5% below the 20-day average ($250.52). Medium term, the picture is negative: the price is 2.0% below the 50-day average ($254.53). Long term, the stock is 8.1% above the 200-day average ($230.71), which confirms a long-term uptrend.

Golden Cross: The 50-day average (254.53) is above the 200-day average (230.71), which is a classic bullish signal for Ascendis Pharma A/S.

Is Ascendis Pharma A/S overbought or oversold?

Ascendis Pharma A/S has an RSI of 46.8, right in the middle of the neutral zone. There is no clear buying or selling pressure.

MACD Analysis for Ascendis Pharma A/S

Daily MACD: MACD is negative (-0.196), which means the short-term trend is bearish (the 12-day EMA is below the 26-day EMA). MACD is below the signal line (-0.080) by 0.116, which confirms growing negative momentum in the downtrend.

Weekly MACD: MACD5 is positive (9.061), which indicates a broader bullish long-term trend. MACD5 is below the signal line (9.538) by 0.477, which suggests the long-term momentum is fading – the positive trend could come under pressure.

Overall MACD assessment: The daily and weekly MACD give conflicting signals. The long-term trend is bullish, but the short-term trend is bearish. Short-term momentum is still falling – a deeper pullback is possible.

Risk Profile for Ascendis Pharma A/S

Ascendis Pharma A/S has an annual standard deviation of 36.7%, which classifies the stock as medium risk. The price can swing noticeably when the market moves.

Overall Technical Conclusion for Ascendis Pharma A/S

Trend: Neutral/mixed.

MACD trend (zero line): Daily bearish (-0.196). Weekly bullish (9.061).

MACD momentum (signal): Daily falling. Weekly falling.

RSI: 46.8 – neutral.

Technical signal: Hold

The signals are mixed – trend and MACD point in different directions. Wait until MACD crosses the zero line in the direction of the trend before acting.

Frequently Asked Questions About Ascendis Pharma stock in 2026

Should you buy Ascendis Pharma stock now?
The technical signal for Ascendis Pharma is currently NEUTRAL. Ascendis Pharma trades at $0.00 as of 8/28/2026. The overall technical signal is: Hold. The technical analysis shows the following: MACD is negative (bearish trend) at -0.196 with falling momentum (signal: -0.080); RSI is at 46.8 (neutral zone). This is a technical observation based on current data, not investment advice.
What is the price target for Ascendis Pharma stock?
There is currently no active analyst price target for Ascendis Pharma.
Is Ascendis Pharma a dividend stock?
No, Ascendis Pharma does not currently pay a dividend to shareholders. The company reinvests its profits in growth instead of paying dividends.
What is the risk of Ascendis Pharma stock?
Ascendis Pharma is rated as a stock in the risk category Moderate. the annual standard deviation is 36.7%, which classifies the stock as Moderate.
Is Ascendis Pharma overvalued?
Ascendis Pharma has the following valuation ratios: a P/E ratio of 19.2 (moderately valued), a P/S ratio of 15.7, a P/B ratio of 9.9.
Is Ascendis Pharma overbought?
No, Ascendis Pharma is not overbought. RSI is at 46.8 (neutral zone). The technical indicators show: RSI is at 46.8 (neutral zone between 30-70), which signals neither overbought nor oversold. In addition, MACD is negative with falling momentum (bearish).
When is the next Ascendis Pharma earnings report?
The date of the next earnings report for Ascendis Pharma has not been published yet. Check the company's investor calendar for updates.
Is Ascendis Pharma shorted?
Yes, Ascendis Pharma is shorted with 6.7% of the free float sold short. This is a high level of short selling, which suggests some investors are betting on falling prices. Positive surprises can lead to a moderate short squeeze. Data is updated daily based on official filings with the SEC.
Are insiders buying Ascendis Pharma stock?
Yes, insiders are net buyers of Ascendis Pharma – they are buying more shares than they are selling. Over the last 3 months, insiders have made 2 purchases and 0 sales. On a net basis, 293,501 $ worth of shares were bought. Across the last 6 reported transactions, the split is 5 purchases and 1 sales, with a net 4,199,110 $ sold. Active buyers include BIENAIME JEAN JACQUES, SMITH SCOTT THOMAS. Insider buying is generally seen as a positive signal, because management is putting its own money into the company.
Is Ascendis Pharma a good stock?
Based on our total score, Ascendis Pharma is rated as a good stock with a total score of 66 out of 100. The stock scores above average on value, quality and momentum – it is among the top 34% in our database. The score is made up of Value: 41/100, Quality: 98/100, Momentum: 58/100. In addition: technical signal: Hold. Whether Ascendis Pharma is a good investment depends on your time horizon, risk profile and portfolio. This is a data-driven observation, not investment advice.
What is the outlook for Ascendis Pharma stock?
The outlook for Ascendis Pharma based on current data: the P/E ratio is 19.2 (moderate). Keep in mind that stock prices are affected by many factors, including earnings reports, the economy and market sentiment. Past returns are no guarantee of future returns.
Why is Ascendis Pharma stock moving?
Ascendis Pharma is moving right now. The technical indicators show: MACD is negative with falling momentum (bearish signal); short interest is 6.7% (high – many are betting on a decline); insiders have mostly been buying the stock recently. For the latest context, see our technical analysis, insider section and news overview above.
How high can Ascendis Pharma go?
There is currently no active analyst price target for Ascendis Pharma. Keep in mind that price targets are estimates, not guarantees. Actual price moves depend on earnings, market conditions and unexpected events.
How low can Ascendis Pharma fall?
We lack enough history to give a specific floor for Ascendis Pharma. Remember: past price swings are no guarantee for the future — a stock can fall further than the last 52 weeks suggest, especially on profit warnings, sector crises or a market crash. Use stop-loss orders and spread your portfolio to limit losses in single stocks.
What does Ascendis Pharma do?
Ascendis Pharma A/S, operates as a biopharmaceutical company that focuses on developing TransCon-based therapies for unmet medical needs in Europe, the United States, and internationally. The company offers SKYTROFA for treating pediatric patients with growth hormone deficienc... The company belongs to the Healthcare sector, more specifically the Bioteknologi industry, is headquartered in USA, and is traded on the USA Stocks. See the key figures, earnings history and price development above to evaluate Ascendis Pharma as an investment.
Did Ascendis Pharma raise or lower its guidance?
Over the last 60 days we have not registered a guidance raise or cut from Ascendis Pharma. The company can still adjust its guidance at quarterly reports or between reports — see the earnings history and the news overview above.
Is Ascendis Pharma making money or losing money?
Yes, Ascendis Pharma is making money, not losing it. The company has a profit margin (the share of revenue left over as profit) of 70.9% — which is excellent. The operating margin (profit before interest and taxes) is 65.0%. At a P/E ratio of 19.2, you currently pay 19.2 dollars for every dollar of the company's annual earnings. A consistently profitable company is usually more resilient than growth stocks that are not yet making money.
Can Ascendis Pharma go bankrupt?
The bankruptcy risk of Ascendis Pharma is rated as moderate. Altman Z2 (a model for assessing financial distress) is 1.93 — that places the company in the middle zone. The Piotroski score (financial health 0-9, higher is better) is 8 — which is strong. Debt relative to equity is 1,000% (high). Remember: models like Altman Z2 are statistical — unexpected shocks (fraud, a sector collapse, lawsuits) can always happen. Spread your portfolio.
Does Ascendis Pharma have a lot of debt?
Yes, Ascendis Pharma has elevated debt relative to equity. The debt-to-equity ratio (D/E — interest-bearing debt to equity) is 1,000%. For the healthcare sector, anything above 150% counts as elevated — that raises the financial risk, especially if interest rates rise or earnings fall. In healthcare, 80-150% is typical — large pharma companies carry debt for research and acquisitions. Note: D/E levels are highly sector-specific — a bank at 300% debt is normal, a tech stock at 300% is extremely leveraged. Always compare with similar companies in the same sector. Can Ascendis Pharma service its debt? Can service its debt without problems — the interest coverage ratio (how many times earnings can cover interest payments) is 4.4x, and the company has more cash than debt (net cash).