Acrivon Therapeutics (ACRV.US) Price Target 2026/2027: 590% Upside – Rating and Stock Analysis

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Price history for Acrivon Therapeutics (ACRV.US) – stock price at 1.67 $, August 2026
Acrivon Therapeutics stock price – price development 2026. Updated Aug 6, 2026.
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Acrivon Therapeutics Price Target 2026: Analysts See 591% Upside

The average price target for Acrivon Therapeutics is $11.50. This price target represents the analysts' view of the stock price over the next 12 months. The stock may be undervalued, because the price target is higher than the current price. The stock is 590,69% below the target, which can point to potential returns within the next 12 months if the analysts' view proves right. Also consider the stock's valuation ratios such as P/E, P/S and P/B, plus the technical analysis further down the page, for the full picture.

Is Acrivon Therapeutics overvalued or undervalued?

Acrivon Therapeutics is currently undervalued with a gap of 590.7% relative to the price target.


The current price is $1.67, which places Acrivon Therapeutics in the undervalued category. The stock is considered undervalued when the price is below $10.35, and overvalued when the price exceeds $12.65.


The fair value range is defined as ±10% of the price target, because price targets are estimates rather than exact values. For Acrivon Therapeutics, the fair value range lies between $10.35 and $12.65.


See the full price target analysis for Acrivon Therapeutics →

Analyst Ratings for Acrivon Therapeutics stock in 2026: Buy

9 analysts cover Acrivon Therapeutics. There is broad agreement on a positive view — 88.8% recommend buying. The average price target is $11.50, which gives an upside of 590.7% from the current price.

Consensus: Buy (4.33/5)
Strong Buy
4 (44.4%)
Buy
4 (44.4%)
Hold
1 (11.1%)
Strong Sell Sell Hold Buy Strong Buy
4.33 out of 5 based on 9 analysts

About Acrivon Therapeutics – Bioteknologi

Acrivon Therapeutics, Inc., a clinical-stage biopharmaceutical company, discovers and develops oncology medicines for patients whose tumors are predicted to be sensitive to each specific medicine by utilizing its generative phosphoproteomics platform. The company operates Acrivon Predictive Precision Proteomics (AP3), a precision medicine platform that enables the creation of drug specific proprietary OncoSignature companion diagnostics that are used to identify the patients to benefit from its drug candidates. Its lead clinical candidate is ACR-368, a selective small molecule inhibitor targeting CHK1 and CHK2 for the treatment of patients with endometrial and platinum-resistant ovarian cancer, and SCCs, such as SCCHN and anal cancer. The company is also developing ACR-2316, a dual WEE1 and PKMYT1 inhibitor small molecule candidate; and a preclinical stage AP3-and co-crystallography-based preclinical cell cycle program. The company was incorporated in 2018 and is based in Watertown, Massachusetts. Read more about the company

Key Figures for Acrivon Therapeutics

$ 66,8M Market cap
- Revenue
Bioteknologi Industry
- P/E
- P/S
0.68 P/B
USA Listed on exchange
Sundhed Sector

What kind of stock is Acrivon Therapeutics?

Speculative stock

Acrivon Therapeutics is classified as a speculative stock.

Score Overview for Acrivon Therapeutics

💰 Value Score 27/100 (Low)
⭐ Quality Score 7/100 (Very Low)
🚀 Momentum Score 14/100 (Very Low)
📊 Total Score 16/100

⚠️ 3 red flags identified 3 critical

Our analysis has identified 3 potential risk factors in Acrivon Therapeutics that investors should be aware of.

🚨 Weak financial health: The Piotroski score is only 1/9 – the company shows signs of weakened profitability, liquidity or capital structure.
🚨 Weak balance sheet (elevated risk): Altman Z2 is -0.58 – the balance sheet is measurably weaker than average. This is a risk signal based on the numbers, not a bankruptcy prediction.
🚨 Negative return on equity: ROE is -60.4% – the company is generating a negative return for shareholders.

📈 Valuation

The P/B ratio is 0.7, below book value, which can point to a value opportunity.

🏦 Financial Health

The Piotroski score is 1 out of 9 — weak financial health, be careful. Altman Z2 is -0.58 (weak balance sheet — elevated risk). The debt-to-equity ratio (D/E) is 11.2% — low debt, a solid balance sheet.

🚀 Momentum & Short Interest

Short interest is 5.19% — elevated, some investors are betting on a decline.

Insider Trading in Acrivon Therapeutics 2026: The Signal Is negative

In 2026, insiders at Acrivon Therapeutics have made 20 transactions – split into 4 purchases and 16 sales. On a net basis, insiders put 7,009,534 $ into the stock, which is a positive signal. Active insiders include RA CAPITAL MANAGEMENT, L.P., Levy Adam D., Blume-Jensen Peter and others. In the short term (last 3 months), the insider signal is negative.

Short-Term Signal (3 months): Negative

Insiders have exclusively sold shares over the last 3 months.

Over the last 3 months: 0 purchases and 7 sales. A net 30,485 $ out of the stock.

Long-Term Signal (all transactions): Mostly positive

Insiders have bought considerably more than they have sold. This suggests several key people see value in the stock.

Across the last 20 transactions: 4 purchases and 16 sales. A net 7,009,534 $ into the stock.

Latest purchase: RA CAPITAL MANAGEMENT, L.P. bought 3,888,888 shares at 2 $ each on 2026-04-22. The stock has since fallen 8.9%.

Latest sale: Miller Mary sold 573 shares at 2 $ each on 2026-07-21.

Who is buying: RA CAPITAL MANAGEMENT, L.P., Levy Adam D., Blume-Jensen Peter, Devroe Eric.

Who is selling: Miller Mary, Blume-Jensen Peter, Peterson Katharine, Gamelin Erick, Devroe Eric.

Latest Insider Trades in Acrivon Therapeutics (2026)

The table shows the last 20 reported insider transactions in Acrivon Therapeutics. Green rows are purchases, red rows are sales. The data is based on official filings.

Transaction date Name Type Number of shares Price per share ($) Total amount ($)
2026-07-21 Miller Mary Sell 573 2 1,008
2026-05-21 Blume-Jensen Peter Sell 13,729 2 24,575
2026-05-14 Peterson Katharine Sell 99 2 190
2026-05-14 Miller Mary Sell 184 2 353
2026-05-14 Gamelin Erick Sell 404 2 776
2026-05-14 Devroe Eric Sell 613 2 1,177
2026-05-14 Blume-Jensen Peter Sell 1,253 2 2,406
2026-04-22 RA CAPITAL MANAGEMENT, L.P. Buy 3,888,888 2 6,999,998
2026-04-17 Miller Mary Sell 558 2 993
2026-02-21 Blume-Jensen Peter Sell 14,265 2 21,825

Who is buying and selling Acrivon Therapeutics shares in 2026?

The following insiders have bought shares in Acrivon Therapeutics: RA CAPITAL MANAGEMENT, L.P., Levy Adam D., Blume-Jensen Peter, Devroe Eric. In total, 7,114,533 $ was bought across 4 transactions. The following insiders have sold shares: Miller Mary, Blume-Jensen Peter, Peterson Katharine, Gamelin Erick, Devroe Eric. In total, 104,999 $ was sold across 16 transactions. Insider trades are legal transactions in which executives and board members buy or sell shares of their own company. These transactions are reported to the SEC and are publicly available.

Acrivon Therapeutics Short Selling 2026: 5.2% Sold Short

High short interest: 5.2% of the free float
Short % of free float
5.2%
Assessment
High short interest
Short squeeze risk
Moderate
Data source
SEC
Updated daily
The stock has a high share of short selling. Between 5-10% of the freely traded shares are sold short, which suggests some investors are betting on falling prices. Positive surprises can lead to a moderate short squeeze.

What does this mean for you as an investor?
A short interest of 5.2% means that 5.2% of the freely traded shares in Acrivon Therapeutics have been borrowed and sold by investors betting on falling prices.

The next potential catalyst is the earnings report on 8/12/2026. With a short interest of 5.2%, the report can trigger considerable volatility.

Data is updated daily based on official filings with the SEC.
Short Interest Scale
0% 2% 5% 10% 20%+
Low Moderate High Very High Extreme
5.2%

When Does Acrivon Therapeutics Report Earnings – Next Date: 8/12/2026

The next earnings report from Acrivon Therapeutics is scheduled for August 12, 2026. This report covers the second quarter (Q2), which ended on June 30, 2026.



Technical Analysis of Acrivon Therapeutics 2026 – Signal: Sell

Overall Technical Signal: Sell

Based on trend analysis (SMA50/SMA200) and MACD trend (positive/negative on a daily + weekly basis). Updated August 6, 2026.

Technical analysis of Acrivon Therapeutics (ACRV.US) – RSI 49, MACD negative (bearish), daily candlestick chart August 2026
Acrivon Therapeutics technical analysis – candlestick chart with RSI and MACD. Updated Aug 6, 2026.

Trend Analysis of Acrivon Therapeutics Inc. Common Stock

Acrivon Therapeutics Inc. Common Stock is in a short-term downtrend. The price of $1.64 is 4.3% below the 20-day average ($1.71). Medium term, the picture is negative: the price is 0.6% below the 50-day average ($1.65). Long term, the stock is 11.8% below the 200-day average ($1.86), which signals a long-term downtrend.

Death Cross: The 50-day average (1.65) is below the 200-day average (1.86), which is a classic bearish signal for Acrivon Therapeutics Inc. Common Stock.

Is Acrivon Therapeutics Inc. Common Stock overbought or oversold?

Acrivon Therapeutics Inc. Common Stock has an RSI of 48.7, right in the middle of the neutral zone. There is no clear buying or selling pressure.

MACD Analysis for Acrivon Therapeutics Inc. Common Stock

Daily MACD: MACD is negative (-0.052), which means the short-term trend is bearish (the 12-day EMA is below the 26-day EMA). MACD is below the signal line (-0.037) by 0.015, which confirms growing negative momentum in the downtrend.

Weekly MACD: MACD5 is negative (-0.059), which indicates a broader bearish long-term trend. MACD5 is above the signal line (-0.067) by 0.008, which suggests the negative long-term momentum is fading – a bigger trend reversal could be ahead.

Overall MACD assessment: Both the daily and weekly trend are bearish (MACD negative). However, momentum shows signs of improving on a weekly basis – a potential trend reversal could be ahead, but it is not confirmed yet.

Risk Profile for Acrivon Therapeutics Inc. Common Stock

Acrivon Therapeutics Inc. Common Stock has an annual standard deviation of 93.5%, which classifies the stock as extreme risk. Only risk-tolerant investors should consider this stock, because the price swings can be very large.

Overall Technical Conclusion for Acrivon Therapeutics Inc. Common Stock

Trend: Neutral/mixed.

MACD trend (zero line): Daily bearish (-0.052). Weekly bearish (-0.059).

MACD momentum (signal): Daily falling. Weekly rising.

RSI: 48.7 – neutral.

Technical signal: Sell

The trend is negative and MACD is below the zero line, which confirms the bearish momentum. Consider reducing the position or setting a stop-loss.

Frequently Asked Questions About Acrivon Therapeutics stock in 2026

Should you buy Acrivon Therapeutics stock now?
No, the technical signal for Acrivon Therapeutics is currently SELL. Acrivon Therapeutics trades at $1.67 as of 8/6/2026. The overall technical signal is: Sell. The technical analysis shows the following: MACD is negative (bearish trend) at -0.052 with falling momentum (signal: -0.037); RSI is at 48.7 (neutral zone); the stock is in a short-term downtrend (price below the 20-day average); the analyst price target of $11.50 points to 590.7% upside. This is a technical observation based on current data, not investment advice.
What is the price target for Acrivon Therapeutics stock?
The average analyst price target for Acrivon Therapeutics is $11.50. The current price is $1.67, which gives an upside of 590.7%. Based on this, the stock is considered undervalued. The fair value range (±10% of the price target) is between $10.35 and $12.65.
Is Acrivon Therapeutics a dividend stock?
No, Acrivon Therapeutics does not currently pay a dividend to shareholders. The company reinvests its profits in growth instead of paying dividends.
What is the risk of Acrivon Therapeutics stock?
Acrivon Therapeutics is rated as a stock with extreme risk. the annual standard deviation is 93.5%, which classifies the stock as extreme risk.
Is Acrivon Therapeutics overvalued?
No, Acrivon Therapeutics is considered undervalued based on the analyst price target (590.7% upside). Acrivon Therapeutics has the following valuation ratios: a P/B ratio of 0.7. The analyst price target suggests that the stock is undervalued by 590.7%.
Is Acrivon Therapeutics overbought?
No, Acrivon Therapeutics is not overbought. RSI is at 48.7 (neutral zone). The technical indicators show: RSI is at 48.7 (neutral zone between 30-70), which signals neither overbought nor oversold. In addition, the price is 2.9% below the 20-day average (short-term downtrend). In addition, MACD is negative with falling momentum (bearish).
When is the next Acrivon Therapeutics earnings report?
Acrivon Therapeutics reports its next earnings on August 12, 2026. The stock currently trades at $1.67.
Is Acrivon Therapeutics shorted?
Yes, Acrivon Therapeutics is shorted with 5.2% of the free float sold short. This is a high level of short selling, which suggests some investors are betting on falling prices. Positive surprises can lead to a moderate short squeeze. Data is updated daily based on official filings with the SEC.
Are insiders buying Acrivon Therapeutics stock?
No, insiders are not buying Acrivon Therapeutics shares – they are net sellers. Over the last 3 months, insiders have made 0 purchases and 7 sales. On a net basis, 30,485 $ worth of shares were sold. Across the last 20 reported transactions, the split is 4 purchases and 16 sales, with a net 7,009,534 $ bought. Active sellers include Miller Mary, Blume-Jensen Peter, Peterson Katharine and others. Insider selling can have several explanations (e.g. planned 10b5-1 sales, portfolio diversification or taxes), but sustained selling by several insiders is worth watching closely.
Is Acrivon Therapeutics a good stock?
Based on our total score, Acrivon Therapeutics is rated as a disastrous stock with a total score of 16 out of 100. The stock scores very low on value, quality and momentum – it is among the worst in our database. The score is made up of Value: 27/100, Quality: 7/100, Momentum: 14/100. In addition: analysts see 590.7% upside to the price target; technical signal: Sell. Whether Acrivon Therapeutics is a good investment depends on your time horizon, risk profile and portfolio. This is a data-driven observation, not investment advice.
What is the outlook for Acrivon Therapeutics stock?
The outlook for Acrivon Therapeutics based on current data: the average analyst price target is $11.50 (+590.7%); the next earnings report is due on 8/12/2026, which can move the price. Keep in mind that stock prices are affected by many factors, including earnings reports, the economy and market sentiment. Past returns are no guarantee of future returns.
Why is Acrivon Therapeutics stock falling?
Acrivon Therapeutics is falling right now. The technical indicators show: the price is 2.9% below the 20-day average; MACD is negative with falling momentum (bearish signal); short interest is 5.2% (high – many are betting on a decline); insiders have mostly been selling the stock recently. For the latest context, see our technical analysis, insider section and news overview above.
How high can Acrivon Therapeutics go?
The average analyst price target for Acrivon Therapeutics is $11.50, which corresponds to a potential gain of 590.7% from the current price of $1.67. Keep in mind that price targets are estimates, not guarantees. Actual price moves depend on earnings, market conditions and unexpected events.
How low can Acrivon Therapeutics fall?
We lack enough history to give a specific floor for Acrivon Therapeutics. Remember: past price swings are no guarantee for the future — a stock can fall further than the last 52 weeks suggest, especially on profit warnings, sector crises or a market crash. Use stop-loss orders and spread your portfolio to limit losses in single stocks.
What does Acrivon Therapeutics do?
Acrivon Therapeutics, Inc., a clinical-stage biopharmaceutical company, discovers and develops oncology medicines for patients whose tumors are predicted to be sensitive to each specific medicine by utilizing its generative phosphoproteomics platform. The company operates Acri... The company belongs to the Sundhed sector, more specifically the Bioteknologi industry, is headquartered in USA, and is traded on the USA Stocks. See the key figures, earnings history and price development above to evaluate Acrivon Therapeutics as an investment.
Did Acrivon Therapeutics raise or lower its guidance?
Over the last 60 days we have not registered a guidance raise or cut from Acrivon Therapeutics. The company can still adjust its guidance at quarterly reports or between reports — see the earnings history and the news overview above.
Is Acrivon Therapeutics making money or losing money?
We have no current profitability data for Acrivon Therapeutics. See the latest report in the earnings history above.
Can Acrivon Therapeutics go bankrupt?
The bankruptcy risk of Acrivon Therapeutics is rated as elevated. Altman Z2 (a model for assessing financial distress) is -0.58 — that places the company in the weak zone. This is a probability based on the numbers, not a verdict — bankruptcy is not imminent. But the balance sheet is measurably weaker than average, so watch the debt, liquidity and possible capital raises. The Piotroski score (financial health 0-9, higher is better) is 1 — which is weak. Debt relative to equity is 11% (low). Remember: models like Altman Z2 are statistical — unexpected shocks (fraud, a sector collapse, lawsuits) can always happen. Spread your portfolio.
Does Acrivon Therapeutics have a lot of debt?
No, Acrivon Therapeutics has low debt relative to equity. The debt-to-equity ratio (D/E — interest-bearing debt to equity) is 11%. For the sundhed sector, anything below 80% counts as low debt. Note: D/E levels are highly sector-specific — a bank at 300% debt is normal, a tech stock at 300% is extremely leveraged. Always compare with similar companies in the same sector.